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. 2023 Nov 22;13:20483. doi: 10.1038/s41598-023-47452-7

Table 5.

ROC curves characteristics for heart rate variability parameters and selected physiological characteristics in never-weaned patients.

SD2/SD1 during SBT SampEn during SBT ShanEn during SBT BMI admission P0.1 before SBT HR during SBT
AUC 0.74 [0.50, 0.97] 0.74 [0.50, 0.99] 0.74 [0.52, 1.0] 0.52 [0.32, 0.73] 0.74 [0.39, 1.0] 0.57 [0.37, 0.77]
Youden’s J 0.52 0.59 0.50 0.20 0.63 0.24
Sensibility 0.86 [0.06,0.87] 0.86 [0.03,0.94] 0.71 [0.07,0.96] 0.44 [0.25, 0.84] 0.80 [0, 1.0] 0.3 [0.48, 0.99]
Specificity 0.66 [0.43, 1.0] 0.73 [0.14, 1.0] 0.79 [0.29, 1.0] 0.75 [0, 0.7] 0.84 [0.4, 1.0] 0.94 [0, 0.6]
Cut-off 1.50 1.63 2.96 22.7 2.5 69.5
PPV 0.14 [0.11, 0.67] 0.17 [0.12, 0.64] 0.18 [0.11, 0.60] 0.12 [0.07, 0.21] 0.27 [0.16, 0.6] 0.30 [0.10, 0.58]
NPV 0.99 [0.96, 1.0] 0.99 [0.96, 1.0] 0.98 [0.96, 1.0] 0.95 [0.94, 1.0] 0.98 [0.95, 1.0] 0.94 [0.93, 1.0]

AUC: area under the curve; PPV: positive predictive value; NPV: negative predictive value; SBT: spontaneous breathing test; SD1: Poincaré plot standard deviation perpendicular the line of identity; SD2: Poincaré plot standard deviation along the line of identity; SampEn: sample entropy; ShanEn: Shanon entropy: Youden’s J: statistic value for performance of dichotomous diagnostic test: Cut-off: best value for the parameter, determined by ROC curve analysis.