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. 2023 Nov 22;13:20438. doi: 10.1038/s41598-023-47675-8

Table 2.

List of primers used in the present study (without including the Illumina adapters67) and thermocycling conditions followed during the first PCRs for eDNA metabarcoding library preparation for each primer set.

Target region Primer (5ʹ–3ʹ) Thermocycling conditions References
Croc_COI COIa: AGTATAAGCGTCTGGGTAGTC Croc_COI: 94 °C (120 s) followed by 35 cycles at 94 °C (45 s), 48 °C (45 s), 72 °C (90 s); and a final extension of 72 °C (10 min) 36,37
COIf: CCTGCAGGAGGAGGAGAYCC
Croc_CR drL15459: AGGAAAGCGCTGGCCTTGTAA Croc_CR: 94 °C (120 s) followed by 33 cycles at 94 °C (30 s), 58 °C (30 s), 72 °C (45 s); and a final extension of 72 °C (7 min) 56
CR2HA: GGGGCCACTAAAAACTGGGGGGA
MiFish (12 S) F: CCGGTAAAACTCGTGCCAGC 12S: 95 °C (180 s), 35 cycles of 98 °C (20 s), 65 °C (15 s), 72 °C (15 s), and a final extension of 72 °C (5 min) 25
R: CATAGTGGGGTATCTAATCCCAGTTTG
VertCOI BloodmealF1_t1: ACCACWATTATTAAYATAAARCCMC VertCOI: 94 °C (120 s) followed by 60 cycles at 94 °C (40 s), 56 °C (40 s), 72 °C (30 s); and a final extension of 72 °C (5 min) 61
BloodmealF2_t1: ACTACAGCAATTAACATAAAACCMC 61
VR1_t1:TAGACTTCTGGGTGGCCAAAGAATCA 60
VR1d_t1:TAGACTTCTGGGTGGCCRAARAAYCA 60
VR1i_t1:TAGACTTCTGGGTGNCCNAANAANCA 60