Skip to main content
. 2023 Nov 22;14:7639. doi: 10.1038/s41467-023-43239-6

Fig. 4. Harnessing the AIMS-enhanced MSC secretome for immunomodulation applications.

Fig. 4

a Heatmap measuring the inflammatory factors secreted from IFN-γ primed MSCs from different groups. bi ELISA assay measuring the secretion of FGF-2, IGF-1, VEGF, HGF-1, IL-6, IL-10, IFN-γ, and TNF- α from different groups after incubating for 4 days. j Flow cytometry analysis measuring the percentage of CD86 and CD163 positive human THP-1 cells after incubating with the conditional medium from MSCs for 2 days. k Flow cytometry analysis measuring the percentage of CD4 positive T cells after incubating with the conditional medium from MSCs for 3 days. l Flow cytometry analysis measuring the B cell proliferation after incubating with the conditional medium from MSCs for 7 days. m, n ELISA assay measuring the secretion of TNF- α and IL-10 from B cells. The statistical analysis was performed using one-way ANOVA with Tukey’s post-hoc test. Data are graphed as the mean ± SD (n = 4 tests, biological repeats). Source data are provided as a Source Data file.