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. 2023 Oct 31;16:171–183. doi: 10.1016/j.sopen.2023.10.008

Table 2.

Study subject end of treatment objective response rates.

Group 1
Group 2
UX first-line therapy (n = 11) UX second-line or above therapy (n = 32) P-value UX first-line therapy (n = 11) NP first-line therapy (n = 60) P-value
Best response, a(n)
CR 1 0 1 1
PR 2 5 2 10
SD 3 7 3 31
PD 3 19 3 18
NA 2 1 2 0
Total 11 32 11 60
ORR,b % 27.27 15.63 0.401 27.27 18.33 0.444
95%Clc 0.060,0.610 0.053,0.328 0.060,0.610 0.095,0.304

CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR objective response rate, CI confidence interval, UX (Utidelone plus Capecitabine); NP (Vinorelbine plus Cisplatin).

a

Assessed according to RECIST1.1.

b

ORR = (CR + PR)/total × 100 %.

c

Calculated using Clopper Pearson method.