Table 2.
Study subject end of treatment objective response rates.
Group 1 |
Group 2 |
|||||
---|---|---|---|---|---|---|
UX first-line therapy (n = 11) | UX second-line or above therapy (n = 32) | P-value | UX first-line therapy (n = 11) | NP first-line therapy (n = 60) | P-value | |
Best response, a(n) | ||||||
CR | 1 | 0 | 1 | 1 | ||
PR | 2 | 5 | 2 | 10 | ||
SD | 3 | 7 | 3 | 31 | ||
PD | 3 | 19 | 3 | 18 | ||
NA | 2 | 1 | 2 | 0 | ||
Total | 11 | 32 | 11 | 60 | ||
ORR,b % | 27.27 | 15.63 | 0.401 | 27.27 | 18.33 | 0.444 |
95%Clc | 0.060,0.610 | 0.053,0.328 | 0.060,0.610 | 0.095,0.304 |
CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR objective response rate, CI confidence interval, UX (Utidelone plus Capecitabine); NP (Vinorelbine plus Cisplatin).
Assessed according to RECIST1.1.
ORR = (CR + PR)/total × 100 %.
Calculated using Clopper Pearson method.