Phylogenetic analysis of interferon induced transmembrane protein 1 (IFITM1) in mammals reveals lineage-specific duplications in white-tailed deer and evolutionary diversification
(A) Alignment of IFITM1 from select boreoeutherian mammals. An extended N-terminal start to XP_043307611.1 (Cervus canadensis) and XP_025142924.2 (Bubalus bubalis) has been trimmed from the alignment. Boxed and asterisked positions 20, 113 and 115 were identified as sites of diversifying selection. Alignment is colored with the Clustal color scheme with poorly conserved residues left white using Jalview v2.11.2.6.
(B) A mid-point rooted tree of IFITM1 from select boreoeutherian mammals. Bootstrap values less than 70 were not displayed. See also Table S9.