Proteome analyses upon GBP1 modulation
Total cell lysates were prepared, and global proteome profiling was performed as described in the STAR Methods section. Gene set enrichment analysis was performed on the proteomics results to determine the enrichment of the Kyoto Encyclopedia of Genes and Genomes pathways upon GBP2b modulation in the ID8 cell line.
(A–C) Enrichment analysis of GBP1-OV ID8 cells compared with VC ID8 cells.
(D–F) Enrichment analysis of GBP1-KD ID8 cells compared with SC ID8 cells.