REAGENT or RESOURCE	SOURCE	IDENTIFIER
Experimental models: Cell lines
ID8	MilliporeSigma	Cat. No. # SCC145; RRID: CVCL_IU14
OVCAR8	NCI-DTP repository	RRID: CVCL_1629
SKOV3	MilliporeSigma	Cat. No. # 91091004; RRID: CVCL_0532
OVCAR3	NCI-DTP repository	RRID: CVCL_0465
HEK293T	ATCC	Cat. No. # CRL-3216; RRID: CVCL_0063
Recombinant DNA
mGBP2b overexpression: pLV{Exp}-mCherry:T2A:Puro-EF1A>mGbp2b{NM_010259.2}	VectorBuilder	Vector ID: VB180117-1093kbb
mGBP2b shRNA: pLV{shRNA}-EGFP:T2A:Puro-U6>mGbp2b{shRNA# TGGGATTGGCATGTTATAAAC}	VectorBuilder	Vector ID: VB180117-1250gdh
hGBP1 overexpression: pLV{Exp}-mCherry:T2A:Puro-EF1A>hGBP1{NM_002053.2}	VectorBuilder	Vector ID: VB170503-1150awy
hGBP1 shRNA: pLV{shRNA}-EGFP:T2A:Puro-U6>hGBP1{shRNA# CCAGATGAGTACCTGACATAC}	VectorBuilder	Vector ID: VB170507-1030ruw
Vector Control: pLV{Exp}-mCherry:T2A:Puro-EF1A>ORF_Stuffer	VectorBuilder	Vector ID: VB230206-1323fan
Scramble shRNA Control: pLV{shRNA}-EGFP:T2A:Puro-U6>Scramble_shRNA {CCTAAGGTTAAGTCGCCCTCG}	VectorBuilder	Vector ID: VB170507-1033npu
Chemicals, peptides, and recombinant proteins
DMEM	Corning	Cat. No. #10-013-CV
RPMI-1640	Corning	Cat. No. #10-040-CV
FBS	Corning	Cat. No. #35-015-CV
Antibiotic-Antimycotic solution	Corning	Cat. No. #15240062
Puromycin	InvivoGen	Cat. No. #ant-pr-1
Paclitaxel	Cayman Chemical	Cat. No. # 10461100
DMSO	MP Biomedicals	Cat. No. #196055
SU093 (NSC756093)	Malhotra lab	Andreoli et al., 201428
Antibodies
GBP1	Abnova	Cat. No. #H00002633-PW1; RRID: AB_10716038
GBP1	Novusbio	Cat. No. # NBP2-03972
β-actin	CST	Cat. No. # 4970S; RRID: AB_2223172
Ub	CST	Cat. No. # 43124S; RRID: AB_2799235
PSMB1	Thermo Scientific	Cat. No. # PA5-49648; RRID: AB_2635102
PSMB6	Thermo Scientific	Cat. No. # PA1-978; RRID: AB_2172197
PSMA3	Proteintech	Cat. No. # 11887-I-AP; RRID: AB_2171420
Rabbit IgG	EMD Millipore	Cat. No. # PP64B; RRID: AB_145841
Anti-mouse IgG HRP-linked antibody	CST	Cat. No. #7076; RRID: AB_330924
Anti-rabbit IgG HRP-linked antibody	CST	Cat. No. #7074; RRID: AB_2099233
Critical commercial assays
M-PER™ lysis solution	Thermo Scientific	Cat. No. #78503
Halt protease and phosphatase inhibitor cocktail	Thermo Scientific	Cat. No. #78440
Tandem Mass Tag (TMT)	Thermo Fisher Scientific	Cat. No. # 90110, Cat. No. #90061
Proteasome Activity Assay kit	Abcam	Cat No. # ab107921
Experimental models: Organisms/strains
C57BL/6J	The Jackson Laboratory	Strain #:000664, RRID: IMSR_JAX:000664
Deposited data
Mass spectrometry proteomics data	PRIDE database	http://www.ebi.ac.uk/pride Dataset identifier: PXD040444 reviewer_pxd040444@ebi.ac.uk
Software and algorithms
GraphPad Prism 9	GraphPad Software	https://www.graphpad.com/