Table 3. π–π Aromatic Interactions between AURKA and the 1,3-Thiazolidine-4-one Derivatives.
compounds | residues | distance | angle | type |
---|---|---|---|---|
5a | Phe 144 | 6.35 | 83.26 | edge-to-facee |
Trp 277 | 6.69 | 58.71 | edge-to-face | |
5b | Tyr 219 | 5.70 | 70.50 | edge-to-face |
5c | Tyr 219 | 4.96 | 71.59 | edge-to-face |
5d | Tyr 219 | 6.37 | 66.84 | edge-to-face |
5e | Tyr 219 | 5.71 | 86.82 | edge-to-face |
5f | Phe 144 | 6.01 | 84.11 | edge-to-face |
Trp 277 | 5.66 | 45.23 | face-to-face | |
5g | Tyr 219 | 5.76 | 81.22 | edge-to-face |
5h | Tyr 219 | 5.94 | 71.94 | edge-to-face |