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. 2023 Nov 6;8(46):43856–43872. doi: 10.1021/acsomega.3c05785

Figure 6.

Figure 6

SASA analysis of ALK WT and I1171N/S/T mutations in Apo and ATP-bound states throughout 200 ns MDS. The X-axis denotes the time in nanosecond, and the Y-axis displays the area in square nanometer. (A) SASA analysis of WT-Apo and WT-ATP, where WT-Apo and WT-ATP are represented in black and navy blue, respectively. (B) SASA analysis of I1171N-Apo and I1171N-ATP, where I1171N-Apo and I1171N-ATP are represented in green and pear, respectively. (C) SASA analysis of I1171S-Apo and I1171S-ATP, where I1171S-Apo and I1171S-ATP are represented in mustard and cyan, respectively. (D) SASA analysis of I1171T-Apo and I1171T-ATP, where I1171T-Apo and I1171T-ATP are represented in red and orange, respectively.