Table 3.
Inbreeding and SROH, the total sum of ROH in modern and ancient European populations for Mb. The data for the Faroe Islands are from the present study in which: (bas., PLINK default), (adv., PLINK default) refers to our basic and advanced filtering, respectively, and the default ROH parameters used in PLINK except for the minimum ROH length (Additional files 2 and 6). The (bas., PLINK [20]), (adv., PLINK [20]) refers to our basic and advanced filtering, respectively, and the same PLINK parameters used in the reference [20] (Additional files 9 and 10). The SROH are mean values rounded to integers and the remaining numbers are rounded to 3 decimal digits
Population/Region | SROH | Ref. | ||||
---|---|---|---|---|---|---|
med | iqr | mean | sd | Mb | ||
Faroe Islands (adv., PLINK default) | 0.036 | 0.017 | 0.042 | 0.019 | 120 | HG |
Faroe Islands (bas., PLINK default) | 0.029 | 0.013 | 0.035 | 0.018 | 101 | HG |
Faroe Islands (adv., PLINK [20]) | 0.018 | 0.011 | 0.023 | 0.015 | 67 | HG |
Faroe Islands (bas., PLINK [20]) | 0.018 | 0.010 | 0.022 | 0.014 | 65 | HG |
Endogamous Dalmatians | 0.013 | 35 | [20] | |||
Endogamous Orcadians | 0.011 | 28 | [20] | |||
Croatians | 0.007 | 18 | [20] | |||
Mixed Dalmatians | 0.006 | 15 | [20] | |||
Mixed Orcadians | 0.005 | 14 | [20] | |||
CEU | 0.003 | 8 | [20] | |||
Scottish | 0.003 | 7 | [20] | |||
Half Orcadians | 0.002 | 6 | [20] | |||
CEU | 0.004 | 0.002 | 13 | [26] | ||
FIN | 0.009 | 0.004 | 26 | [26] | ||
GBR | 0.006 | 0.004 | 17 | [26] | ||
IBS | 0.006 | 0.005 | 18 | [26] | ||
TSI | 0.005 | 0.003 | 13 | [26] | ||
Hunter-gatherers | 0.063 | 0.026 | [25] | |||
Simple agriculturalists | 0.029 | 0.014 | [25] | |||
- West Eurasia | 0.029 | 0.012 | [25] | |||
- Central Eurasia | 0.020 | 0.017 | [25] | |||
Early comp. agriculturalists | 0.025 | 0.011 | [25] | |||
- West Eurasia | 0.024 | 0.010 | [25] | |||
- Central Eurasia | 0.027 | 0.011 | [25] | |||
Adv. comp. agriculturalists | 0.016 | 0.009 | [25] | |||
- West Eurasia | 0.021 | 0.006 | [25] | |||
- Central Eurasia | 0.015 | 0.006 | [25] | |||
Human Genome Div. Panel | 0.007 | 0.022 | [25] | |||
- West Eurasia | 0.004 | 0.005 | [25] | |||
- Central Eurasia | 0.016 | 0.034 | [25] | |||
European ancestry | 0.009 | 0.011 | 0.007 | 32 | [27] |