Skip to main content
. 2023 Nov 23;12:RP91645. doi: 10.7554/eLife.91645

Figure 2. Analysis of human protein coverage by antibodies.

Figure 2.

(A) Cumulative plot showing the percentage of the human proteome that is covered by polyclonal antibodies (blue line) and renewable antibodies (monoclonal +recombinant; orange line). The number of antibodies per protein was extracted from the Antibody Registry database. (B) Percentage of target proteins covered by minimally one renewable successful antibody (orange column) or covered by only successful polyclonal antibodies (blue column) is shown for each indicated applications using a bar graph. Lack of successful antibody (‘none’) is also shown (black column).

Figure 2—source data 1. Number of antibodies per human protein.
The Antibody Registry was queried with a set of Uniprot-derived protein names representing 16,262 human proteins. The number of polyclonal and monoclonal antibodies (representing recombinant and mouse monoclonal antibodies) that match the protein list is shown.