Table 3.
Pycard C/T (rs8056505) Genotype Distribution, Allele Frequencies and Hardy-Weinberg Equilibrium Between Control Group and Periodontitis, Atherosclerotic with Health Periodontium and Atherosclerotic with Periodontitis Patients’ Groups
| Genotype | Control n=30 | Perio n=30 | P value | O.R (95% Cl) | AS n=30 | P value | O.R (95% Cl) | AS-P n=30 | P value | O.R (95% Cl) |
|---|---|---|---|---|---|---|---|---|---|---|
| CC | 24 (80%) | 2 (7%) | 0.00** | 56.0 (11.19 to 260.6) | 1 (3%) | 0.000** | 116.0 (14.65 to 122) | 0 (0%) | 0.000** | 229.9 (12.335 to 4285.42) |
| CT | 2 (7%) | 12 (40%) | 0.0023** | 0.107 (0.022 to 0.470) | 10 (33%) | 0.0098** | 0.1429 (0.02970 to 0.6584) | 17 (57%) | 0.000** | 0.054 (0.0117 to 0.2757) |
| TT | 4 (13%) | 16 (53%) | 0.001** | 0.134 (0.043 to 0.470) | 19 (64%) | 0.00** | 0.089 (0.02906 to 0.3163) | 13 (43%) | 0.0099** | 0.2012 (0.06497 to 0.720) |
| C Allele | 0.8 (50) | 0.26 (16) | 0.000* | 13.75 (5.51 to 31.65) | 0.2 (12) | 0.000** | 20.0 (7.49 to 47.73) | 0.3 (17) | 0.000** | 12.65 (5.131 to 29.64) |
| T Allele | 0.2 (10) | 0.74 (44) | 0.000** | 13.75 (5.51 to 31.65) | 0.8 (48) | 0.000** | 20.0 (7.49 to 47.73) | 0.7 (43) | 0.000** | 12.65 (5.131 to 29.64) |
| HWE X2 | 0.000 | 0.000 | 4.646 | 0.000 | ||||||
| p value | 0.999 NS | 0.999 NS | 0.098 NS | 0.999 NS | ||||||
Notes: *significant at p ≤ 0.05, **significant p ≤ 0.01.
Abbreviations: n, number; C, Cytosine; T, Thiamin; OR, Odds ratio; 95% Cl, 95% confidence interval; HWE X2, Hardy-Weinberg Equilibrium chi-square; NS, Non-significant.