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. 2023 Sep 21;29(11):2775–2784. doi: 10.1038/s41591-023-02551-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Box plots (n = 100 model replicates per policy, median line with IQR) and violin plots (full data range) show the projected 561H frequency, after 5 years, under 17 policy options and the status quo of continued usage of 3-d AL. Box-plot whiskers show 1.5× IQR, and all outliers (outside 1.5× IQR) are plotted individually as diamonds. The first section includes the status quo and changes to the first-line therapies, followed by the second section containing MFT approaches, then custom drug rotation strategies and finally triple artemisinin combination therapies.