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. 2023 Nov 23;13:20610. doi: 10.1038/s41598-023-47106-8

Table 1.

Description of the characteristics of the study population by COVID-19 vaccine uptake.

Characteristics Total No vaccine 2 or Less vaccines 3 or More vaccinesA
N = 1885 N = 179 (10%) N = 697 (37%) N = 1009 (54%)
Age (median, IQR) 50.1 (41.5–58.3) 47.2 (40.5–57.7) 46.0 (38.6–52.5) 54.0 (43.9–61.4)
< 40 years 406 (22%) 42 (23%) 204 (29%) 160 (16%)
40–50 years 531 (28%) 56 (31%) 254 (36%) 221 (22%)
50–60 years 564 (30%) 51 (28%) 180 (26%) 333 (33%)
> 60 years 384 (20%) 30 (17%) 59 (8%) 295 (29%)
Birth sex
 Male 1356 (72%) 120 (67%) 418 (60%) 818 (81%)
 Female 529 (28%) 59 (33%) 279 (40%) 191 (19%)
Ethnicity/race
 Non-Hispanic white 893 (47%) 95 (53%) 206 (30%) 592 (59%)
 Non-Hispanic black 542 (29%) 48 (27%) 325 (47%) 169 (17%)
 First nations 117 (6%) 12 (7%) 57 (8%) 48 (5%)
 Other/unknownB 333 (18%) 24 (13%) 109 (16%) 200 (20%)
HIV acquisition risk category
 MSM/Bisexual 782 (41%) 47 (26%) 166 (24%) 569 (56%)
 Heterosexual 835 (44%) 94 (53%) 419 (60%) 322 (32%)
 PWID 148 (8%) 23 (13%) 56 (8%) 69 (7%)
 Other/unknownC 120 (6%) 15 (8%) 56 (8%) 49 (5%)
Nadir CD4 category
 > 500 cells/mm3 175 (9%) 23 (13%) 71 (10%) 81 (8%)
 200–500 cells/mm3 857 (45%) 79 (44%) 328 (47%) 450 (45%)
 < 200 cells/mm3 849 (45%) 75 (42%) 297 (43%) 477 (47%)
 Missing 4 (0%) 2 (1%) 1 (0%) 1 (0%)
CD4 category
 > 500 cells/mm3 880 (47%) 65 (36%) 309 (44%) 506 (50%)
 200–500 cells/mm3 682 (36%) 53 (30%) 252 (36%) 377 (37%)
  < 200 cells/mm3 115 (6%) 12 (7%) 59 (8%) 44 (4%)
 Not measured over study period 208 (11%) 49 (27%) 77 (11%) 82 (8%)
Viral load category
 < 200 copies/mL 1635 (87%) 111 (62%) 580 (83%) 944 (94%)
 ≥ 200 copies/mL 137 (7%) 30 (17%) 72 (10%) 35 (3%)
 Not measured over study period 113 (6%) 38 (21%) 45 (6%) 30 (3%)
Ever incarcerated 110 (6%) 15 (8%) 52 (7%) 43 (4%)
Initial vaccine type
 Moderna 409 (22%) 0 (0%) 195 (28%) 214 (21%)
 Pfizer-BioNTech 1297 (69%) 0 (0%) 502 (72%) 795 (79%)
Education level
 < 12 years 352 (19%) 44 (25%) 172 (25%) 136 (13%)
 12 years 426 (23%) 47 (26%) 169 (24%) 210 (21%)
 > 12 years 906 (48%) 55 (31%) 264 (38%) 587 (58%)
 Missing/unknown 201 (11%) 33 (18%) 92 (13%) 76 (8%)
LocationD
 Metropolitan 1495 (79%) 126 (70%) 566 (81%) 803 (80%)
 Non-Metropolitan 374 (20%) 50 (28%) 126 (18%) 198 (20%)
 Missing 16 (1%) 3 (2%) 5 (1%) 8 (1%)
Housing status
 Unstable housing/homeless 182 (10%) 24 (13%) 74 (11%) 84 (8%)
Body mass index
 < 25 kg/m2 544 (29%) 57 (32%) 190 (27%) 297 (29%)
 ≥ 25 kg/m2 1034 (55%) 85 (47%) 354 (51%) 595 (59%)
 Missing 307 (16%) 37 (21%) 153 (22%) 117 (12%)
History of substance use 261 (14%) 36 (20%) 93 (13%) 132 (13%)
Comorbidities
 Malignancy 155 (8%) 12 (7%) 35 (5%) 108 (11%)
 Hypertension 240 (13%) 17 (9%) 64 (9%) 159 (16%)
 Renal disease 61 (3%) 4 (2%) 15 (2%) 42 (4%)
 Cardiovascular disease 64 (3%) 4 (2%) 12 (2%) 48 (5%)
 Asthma or COPD 201 (11%) 19 (11%) 55 (8%) 127 (13%)
 Diabetes mellitus 163 (9%) 7 (4%) 54 (8%) 102 (10%)

IQR—Interquartile range, MSM—men who have sex with men, PWID—people who use injection drugs, COPD—chronic obstructive pulmonary disease.

ABooster dose defined as receiving 3 or more COVID-19 vaccinations.

BOther Ethnicity/Race includes Hispanic, East-Asian, West-Asian, Indo-Asian, or other.

COther HIV risk acquisition group includes blood transfusion, hemophilia or perinatal transmission.

DLocation defined as most recent place of residence, metropolitan and non-metropolitan (city of > 1 million people) or rural (< 1 million people).