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. 2023 Nov 23;29(11):e13522. doi: 10.1111/srt.13522

TABLE 1.

Inclusion and exclusion criteria for enrollment of the study participants.

Inclusion criteria Exclusion criteria
  • Healthy females between 39 to 65 years of age at the time of enrollment.

  • Able to understand and willing to complete a brief personal history, review and sign an informed consent document, and follow all study instructions.

  • Lines/wrinkles in the periorbital area with a score greater than 2 cm and less than 8 cm on a standard 10 cm visual analog scale (VAS).

  • Willing to come to the observation site without makeup.

  • Willing to continue use of all regular brands of color cosmetics provided they do not make any moisturizing or anti‐aging claims.

  • Willing to refrain from using new facial products other than the assigned test materials.

  • Pregnant, breast‐feeding, or planning a pregnancy during the course of the study.

  • Initiated the use of topical or oral prescription steroids and/or anti‐inflammatory medications within 30 days of study enrollment.

  • Participating in any other clinical studies.

  • Known allergies to personal care product(s) (self‐reported).

  • History of sensitivity to skin treatment products.

  • Any dermatologic disorders that may interfere with evaluation of test product performance.

  • Any condition(s) apparent at entry or recognized after entry that are likely to invalidate a subject's consent to participate in this study and/or limit the ability of a subject to regularly attend all study visits or to comply with all other protocol requirements such as: diseases, injuries, alcoholism, drug abuse, psychosis, antagonistic personality, poor motivation, infirmity disability, other problems that may be emotional, intellectual, psychological or social.

  • An employee of the testing facility or other testing firms/laboratories, cosmetic or raw goods manufacturers or suppliers.