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. 2023 Nov 23;15(4):e12503. doi: 10.1002/dad2.12503

FIGURE 1.

FIGURE 1

Representative FLAIR slice illustrating each SSAE‐3 and SSAE‐5 severity level. (A) Monofocal right occipital occurrence <5 cm, corresponding to mild severity on both SSAE‐3 and SSAE‐5 scales. (B) Multifocal right and left occipital occurrences, each <5 cm, corresponding to moderate severity with SSAE‐3 and mild+ severity with SSAE‐5. (C) Monofocal left occipital occurrence of 5–10 cm in greatest dimension, classified as moderate on both SSAE‐3 and SSAE‐5 scales. (D) Multifocal right and left occipital occurrences, the largest being 5–10 cm, corresponding to moderate severity with SSAE‐3 and moderate+ severity with SSAE‐5. (E) Large ARIA‐E occurrence >10 cm in the right hemisphere, expanding across multiple brain territories, together with a smaller occurrence in the left frontal lobe. Irrespective of the number of regions involved, this is scored severe with both scales due to its largest extent. ARIA‐E, amyloid‐related imaging abnormalities–edema; FLAIR, fluid‐attenuated inversion recovery; SSAE, severity scale of ARIA‐E.