TABLE 1.

Information on whole-transcriptome data in ESCC patients from one in-house study and 11 publicly available studies.

Study accession	Number of samples (tumor:adjacent) a	Geographic position	Layout	Sequencing library	Data accession
PRJCA017448	64:63	China	Paired	dUTP	https://ngdc.cncb.ac.cn/search/?dbId=hra&q=PRJCA017448
PRJNA793370	3:3	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/793370
PRJNA843947	6:6	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/843947
PRJNA784605	4:4	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/784605
PRJNA665149	18:18	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/665149
PRJNA689307	8:8	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/689307
PRJNA629358	10:10	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/629358
PRJNA594797	3:3	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/594797
PRJNA608223	0:25	Kazakhstan	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/608223
PRJNA533799	23:23	Korea	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/533799
PRJNA435587	7:7	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/435587
PRJNA298963	15:15	China	Paired	dUTP	https://www.ncbi.nlm.nih.gov/bioproject/298963

^a The number of samples on tumor tissues versus the number of samples on adjacent normal tissues for ESCC patients in each study.