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. 2023 Nov 23;9:73. doi: 10.1186/s40942-023-00498-1

Table 5.

Neural device characteristics

Device Electrode specifications Size Advantages SAE/AEs Clinical Status
ORION 60 electrodes Information not available

- Treats a wider

variety of diseases

- Neural placement

- Ability to navigate

the environment

- Seizure

- Bilateral Hand twitch

- Headache

- Visual Aura

- Visual Phenomenon

Ongoing clinical trials evaluating the safety of the device and surgery
CORTIVIS 100 electrodes (1.0–1.5 mm in length) 4 mm x 4 mm base Information not available Information not available In clinical trial for severe visual impairment with bilateral visual loss
ICVP 16 electrodes per module 2 mm x 2 mm

- No wires or

connectors cross the scalp due to wireless nature

- Camera images are

communicated directly to brain

Information not available In clinical trials to test the safety of the ICVP system and the feasibility of eliciting visual percepts in response to electrical stimulation in persons with blindness
AV-DONE 7 stimulation electrodes (50 µm diameter)

- The rod: 100 μm

diameter

- Cylindrical silicone

board diameter: 2.0 mm. of the active tips of the stimulation electrodes is uncoated. The wires run parallel to each other. Scale bar = 1 mm

- Easy access to the

optic nerve

- Stimulate a wide

visual field

- Elicit small to large

phosphenes using just one stimulating electrode

Information not available Clinical study completed for 1 patient with RP