Table 3.

Late time-point miRNA expression.

(A)
miRNA	n	Survivors	n	Non-survivors	p value	AUC (95% CI)
miR-103	96	29.80 (0.28)	84	29.81 (0.29)	0.80
miR-122	96	30.42 (0.57)	83	30.14 (0.91)	0.01*	0.63 (0.54–0.71)
miR-140	85	28.59 (0.59)	75	28.57 (0.49)	0.75
miR-149	5	27.23 (1.65)	16	27.19 (1.11)	0.96
miR-150	96	30.05 (0.42)	84	30.13 (0.43)	0.19
miR-16-2	61	27.78 (0.74)	37	27.42 (0.93)	0.04	0.60 (0.49–0.73)
miR-17	5	26.04 (0.77)	16	26.34 (0.73)	0.44
miR-191	66	29.55 (0.31)	81	29.57 (0.37)	0.69
miR-200b	14	26.83 (0.65)	15	26.88 (1.37)	0.88
miR-21	96	30.97 (0.46)	84	30.80 (0.44)	0.01*	0.62 (0.54–0.70)
miR-221	89	28.75 (0.55)	79	28.70 (0.60)	0.55
miR-23a	96	30.49 (0.18)	84	30.46 (0.20)	0.42
miR-24	96	29.66 (0.32)	84	29.60 (0.34)	0.27
miR-26	96	29.55 (0.27)	84	29.56 (0.26)	0.73
miR-27a	96	29.07 (0.53)	82	29.14 (0.53)	0.40
miR-29b	25	26.45 (1.17)	26	25.94 (0.98)	0.09
miR-30a	94	28.67 (0.58)	82	28.90 (0.55)	0.008*	0.61 (0.52–0.69)
miR-4270	53	27.54 (1.06)	33	27.45 (1.13)	0.71
miR-503	24	27.37 (0.73)	20	26.32 (1.43)	0.003*	0.74 (0.59–0.90)
miR-663	32	27.25 (1.30)	29	26.83 (1.15)	0.18

(B)
miRNA	OR (95% CI)	p value
miR-149	4.28 (1.61–11.00)	0.005*
miR-16-2	0.45 (0.25–0.82)	0.01*
miR-17	4.28 (1.61–11.00)	0.005*
miR-191	12.27 (3.72–29.27)	<0.0001*
miR-200b	1.27 (0.60–2.75)	0.69
miR-20a	4.27 (0.90–20.66)	0.08
miR-29	1.27 (0.66–2.49)	0.51
miR-330	3.62 (0.87–17.90)	0.15
miR-4270	0.53 (0.28–0.95)	0.07
miR-503	0.94 (0.47–1.82)	0.86
miR-663	1.06 (0.58–1.92)	0.88

(A) Results of t tests between survivors and non-survivors. Results given as mean (SD). If p values <0.05, AUC was calculated. (B) For miRNA detected in <85% of samples at the early time-point, reanalysis was performed after converting results to either detected (1) or undetected (0) using Fisher’s exact test – OR for mortality. Statistical significance set as per Benjamini-Hochberg procedure with a false discovery rate of 0.05 (*p <0.026). miR/miRNA, microRNA; OR, odds ratio.