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. 2023 Oct 26;12(11):1914. doi: 10.3390/antiox12111914

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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ZYAN1 mitigated photoreceptor cell death and ROS production in RD model at P28. (A) The density of GS immunostaining in RD + ZYAN1 group increased significantly compared with that in RD group. (B) The number of TUNEL-positive apoptotic cells in RD + ZYAN1 group reduced significantly compared with that in RD group. The white arrows represent TUNEL-positive cells. (C) The fluorescence intensity of DHE in RD + ZYAN1 group reduced significantly compared with that in RD group (**** p < 0.0001 for differences compared with normal control group; ^#p < 0.05, ^## p < 0.01, ^### p < 0.001, ^#### p < 0.0001 for differences compared with RD + ZYAN1 group, n = 6).