Figure 6.

Model prediction results of the gastric pH profiles over time after a single oral exposure to a 10 mg rabeprazole enteric-coated tablet. Prediction results were presented separately for total (A) without stratification and for males (B) and females (C), separately and stratified by gender. The 50th percentiles of the predicted pH values are represented by black dashed lines and the 95% confidence intervals for the predicted 50th percentiles are represented by the red-shaded regions. The green dotted lines in the graph represent the reference value for 4, the pH rise point established as the effective treatment effect of rabeprazole.