Table 2.
Univariable associations between patient characteristics and CMV.
N | n (%) with CMV | Hazard Ratio (95% Confidence Interval) |
p-Value | |
---|---|---|---|---|
Overall | 102 | 37 (36.3) | -- | |
Age, 5-year increase | -- | -- | 0.95 (0.80–1.13) | 0.52 |
Age | ||||
<65 | 54 | 21 (38.9) | 1 (ref) | 0.62 |
≥65 | 48 | 16 (33.3) | 0.85 (0.44–1.62) | |
Race/ethnicity | ||||
African American | 67 | 27 (40.3) | 1 (ref) | 0.58 |
White | 27 | 7 (25.9) | 0.66 (0.27–1.41) | |
Other | 8 | 3 (37.5) | 0.81 (0.22–2.16) | |
Cause of ESRD | ||||
Diabetes | 46 | 18 (39.1) | 1 (ref) | 0.11 |
Hypertension | 26 | 13 (50.0) | 1.30 (0.63–2.60) | |
Other | 30 | 6 (20.0) | 0.50 (0.19–1.16) | |
Transplant type | ||||
DDKT | 28 | 13 (46.4) | 1 (ref) | 0.02 |
DCD | 71 | 22 (31.0) | 1.62 (0.80–3.14) | |
LKT | 3 | 2 (66.7) | 5.07 (1.01–16.3) | |
History of hepatitis C | ||||
No | 73 | 26 (35.6) | 1 (ref) | 0.89 |
Yes | 29 | 11 (37.9) | 0.95 (0.46–1.87) | |
History of hepatitis B | ||||
No | 93 | 34 (36.6) | 1 (ref) | 0.97 |
Yes | 9 | 3 (33.3) | 1.02 (0.28–2.69) | |
Immunologic risk | ||||
No | 92 | 34 (37.0) | 1 (ref) | 0.96 |
Yes | 10 | 3 (30.0) | 0.97 (0.26–2.57) | |
CMV risk | ||||
1 | 6 | 0 (0.0) | 1 (ref) | 0.28 |
2 | 48 | 17 (35.4) | ||
3 | 48 | 20 (41.7) | 1.41 (0.75–2.71) | |
cPRA > 0 | ||||
0 | 94 | 33 (35.1) | 1 (ref) | 0.38 |
>0 | 8 | 4 (50.0) | 1.54 (0.50–3.73) | |
Donor age, 5-year increase | -- | -- | 1.05 (0.93–1.19) | 0.44 |
Donor age | ||||
<40 | 45 | 15 (33.3) | 1 (ref) | 0.56 |
≥40 | 57 | 22 (38.6) | 1.21 (0.64–2.36) | |
KDPI, 10-point increase | -- | -- | 1.10 (0.96–1.27) | 0.17 |
KDPI | ||||
<50 | 45 | 13 (28.9) | 1 (ref) | 0.32 |
≥50 | 54 | 22 (40.7) | 1.40 (0.72–2.83) | |
Induction | ||||
<4 mg/kg | 31 | 13 (41.9) | 1 (ref) | 0.18 |
>4 mg/kg | 38 | 17 (44.7) | 1.06 (0.52–2.20) | |
Basiliximab | 33 | 7 (21.2) | 0.50 (0.19–1.20) | |
Delayed graft function | ||||
No | 71 | 28 (39.4) | 1 (ref) | 0.44 |
Yes | 31 | 9 (29.0) | 0.75 (0.34–1.52) |