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. 2023 Nov 15;11(11):3060. doi: 10.3390/biomedicines11113060

Table 3.

Univariable associations between patient characteristics and BKPyV.

N n (%) with BKPyV Hazard Ratio
(95% Confidence Interval)
p-Value
Overall 102 18 (17.6) --
Age, 5-year increase -- -- 1.04 (0.81–1.36) 0.77
Age
   <65 54 11 (20.4) 1 (ref) 0.44
   ≥65 48 7 (14.6) 0.69 (0.26–1.76)
Race/ethnicity
   African American 67 8 (11.9) 1 (ref) 0.03
   White 27 6 (22.2) 2.05 (0.67–5.91)
   Other 8 4 (50.0) 4.43 (1.18–14.1)
Cause of ESRD
   Diabetes 46 10 (21.7) 1 (ref) 0.26
   Hypertension 26 2 (7.7) 0.30 (0.05–1.16)
   Other 30 6 (20.0) 0.91 (0.31–2.46)
Transplant type
   DDKT 71 12 (16.9) 1 (ref)
   DCD 28 6 (21.4) 1.21 (0.46–3.16) 0.88
   LKT 3 0 (0.0) --
History of hepatitis C
   No 73 11 (15.1) 1 (ref) 0.32
   Yes 29 7 (24.1) 1.62 (0.59–4.13)
History of hepatitis B
   No 93 17 (18.3) 1 (ref) 0.82
   Yes 9 1 (11.1) 0.83 (0.09–3.27)
Immunologic risk
   No 92 13 (14.1) 1 (ref) 0.004
   Yes 10 5 (50.0) 4.13 (1.32–11.0)
CMV risk
   1 6 1 (16.7) 1 (ref) 0.96
   2 48 9 (18.8) 0.99 (0.19–18.2)
   3 48 8 (16.7) 0.86 (0.16–15.9)
cPRA > 0
   0 94 14 (14.9) 1 (ref) 0.005
   >0 8 4 (50.0) 4.34 (1.23–12.14)
Donor age, 5-year increase -- -- 0.94 (0.78–1.13) 0.53
Donor age
   <40 45 9 (20.0) 1 (ref) 0.62
   ≥40 57 9 (15.8) 0.79 (0.31–2.03)
KDPI, 10-point increase -- -- 1.03 (0.85–1.26) 0.75
KDPI
   <50 45 8 (17.8) 1 (ref) 0.94
   ≥50 54 10 (18.5) 1.04 (0.41–2.71)
Induction
   <4 mg/kg 31 5 (16.1) 1 (ref) 0.97
   >4 mg/kg 38 7 (18.4) 1.03 (0.33–3.50)
   Basiliximab 33 6 (18.2) 1.14 (0.34–3.97)
Delayed graft function
   No 71 11 (15.5) 1 (ref) 0.39
   Yes 31 7 (22.6) 1.51 (0.56–3.84)