PH |
Pulmonary hypertension |
Nrf2 |
Nuclear factor erythroid 2-related factor 2 |
VSMC |
vascular smooth muscle cell |
PAEC |
pulmonary arterial endothelial cell |
PASMC |
pulmonary arterial smooth muscle cell |
PAH |
Pulmonary arterial hypertension |
ROS |
reactive oxygen species |
NOS |
nitric oxide synthase |
NADPH |
nicotinamide adenine dinucleotide phosphate |
SOD |
superoxide dismutase |
ET-1 |
endothelin-1 |
PGI2 |
prostacyclin |
EC |
endothelial cell |
SMC |
smooth muscle cell |
EMT |
epithelial-mesenchymal transition |
NO |
nitric oxide |
EDHF |
endothelium-derived hyperpolarizing factor |
VGCC |
Voltagegated calcium channels |
MCT |
monocrotaline |
NHE |
Na+/H+ exchanger |
ARE |
antioxidant response element |
EpRE |
electrophile response element |
GST |
glutathione S-transferase |
GCL |
glutamate-cysteine ligase |
GPx |
glutathione peroxidase |
TXNRD |
thioredoxin reductase |
TXN |
thioredoxin |
GSH |
glutathione |
sMAF |
small musculoaponeurotic fibrosarcoma |
cAMP |
cyclic adenosine monophosphate |
β-TrCP |
β-transducin repeat-containing protein |
RXR-α |
retinoic X receptor alpha |
Keap1 |
Kelch-like ECH-associated protein 1 |
BTB |
Bric-a-Brac domain |
IVR |
intervening region |
LncRNA |
long non-coding RNA |
RVH |
right ventricular hypertrophy |
SFN |
sulforaphane |
KCNK3 |
potassium channel subfamily K member 3 |
Ipt |
Iptakalim |
PPARγ |
peroxisome proliferator gamma |
DMF |
Dimethyl Fumarate |
RVSP |
right ventricular systolic pressure |
SuHx |
SU5416 and 10% hypoxia |
GCL |
glutamate-cysteine ligase |
RV/(LV+S) |
right ventricular hypertrophy index |