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. 2023 Nov 7;12(11):1975. doi: 10.3390/antiox12111975

Table 1.

Effects of dietary silybin supplementation on growth performance and diarrhea incidence in weaned piglets (trial 1) 1.

Item Silybin Level, mg/kg SEM p-Value
0 50 100 200 400 ANOVA Linear Quadratic
BW, kg
Day 0 8.28 8.28 8.28 8.28 8.28 0.49 1.00 1.00 1.00
Day 14 10.39 10.60 10.57 10.23 11.00 0.53 0.88 0.51 0.59
Day 28 16.05 16.05 15.85 16.18 16.51 0.81 0.99 0.62 0.84
Day 42 23.33 23.42 23.63 24.41 24.80 1.12 0.86 0.28 0.88
ADG 2, g
Day 0–14 151 166 164 140 194 16.76 0.25 0.15 0.23
Day 14–28 404 389 377 422 394 26.05 0.82 0.92 0.86
Day 28–42 520 526 556 588 592 25.53 0.20 0.03 0.34
Day 0–42 358 360 366 388 393 17.56 0.54 0.11 0.73
ADFI 3, g
Day 0–14 270 297 280 262 316 22.26 0.47 0.29 0.36
Day 14–28 659 674 671 700 692 29.66 0.90 0.43 0.62
Day 28–42 996 927 963 1038 977 38.63 0.46 0.68 0.61
Day 0–42 642 633 638 672 662 26.63 0.86 0.42 0.75
FCR 4
Day 0–14 1.81 1.86 1.72 1.96 1.65 0.11 0.30 0.34 0.23
Day 14–28 1.67 1.74 1.79 1.68 1.78 0.08 0.77 0.53 0.89
Day 28–42 1.92 a,x 1.77 ab 1.74 ab,y 1.77 ab 1.65 b 0.05 0.02 0.00 0.35
Day 0–42 1.80 1.76 1.75 1.74 1.68 0.03 0.24 0.03 0.91
DI 5, %
Day 0–14 8.93 a 5.36 ab 6.55 a 7.32 a 2.98 b - 0.02 - -

SEM = standard error of the mean; BW = body weight. 1 Six replicates per treatment (n = 6), four piglets per replicate; the total number of animals is 120. 2 Average daily gain (ADG) = body weight gain of the pen/piglets’ number/days. 3 Average daily feed intake (ADFI) = feed intake of the pen/piglets’ number/days. 4 Feed conversion ratio (FCR) = feed intake of the pen/body weight gain of the pen. 5 Diarrhea incidence (DI), % = the number of piglets with diarrhea/the total number of weaned piglets × 100%. a,b Values within a row without common letters differ significantly (p < 0.05). x,y Values listed in the same row with different superscripts tend to be different (0.05 ≤ p < 0.1).