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. 2023 Oct 28;12(11):1380. doi: 10.3390/biology12111380

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Psychedelics exert their effects through various levels of analysis, including the molecular/cellular, the circuit/network, and the overall brain. The crystal structure of serotonin 2A receptor in complex with LSD is sourced from the RCSB Protein Data Bank (RCSB PDB) [62]. LSD, lysergic acid diethylamide; 5-HT2A, serotonin 2A; CSTC, cortico-striato-thalamo-cortical [63]; REBUS, relaxed beliefs under psychedelics model [64]; CCC, claustro-cortical circuit [65]. Generated using Biorender, https://biorender.com/, accessed on 4 September 2023.