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. 2023 Oct 24;13(11):1572. doi: 10.3390/biom13111572

Table 1.

The general characteristic of poliketides having antifungal activity.

Compound Class No. Compound Name Source Target References
Macrolide
polyketides
1 Amphidinin Q dinoflagellates Amphidinium species (2012-7-4A strain) C. albicans MIC = 32 μg/mL [19]
2 Amphidinin C dinoflagellates Amphidinium species (2012-7-4A strain) A. niger MIC = 32 μg/mL [19]
3 Amphidinin E dinoflagellates Amphidinium species (2012-7-4A strain) A. niger MIC =16 μg/mL [19]
4 Rustmicin Micromonospora narashinoensis 980-MC C. neoformans MY2062 MIC = 0.0001 μg/mL
C. neoformans ATCC9011 MIC = 0.063 μg/mL
C. tropicalis MY1012 MIC = 0.05 μg/mL
C. albicans MY1055 MIC = 6.25 μg/mL
C. albicans ATCC90028 MIC = 4 μg/mL
[22,23]
5 - - C. neoformans ATCC9011 MIC = 0.5 μg/mL
C. albicans ATCC90028 MIC = 64 μg/mL
[23]
6 - - C. neoformans ATCC9011 MIC > 64 μg/mL
C. albicans ATCC90028 MIC > 64 μg/mL
[23]
7 - - C. neoformans ATCC9011 MIC = 32 μg/mL
C. albicans ATCC90028 MIC > 64 μg/mL
[23]
8 - - C. neoformans ATCC9011 MIC = 16 μg/mL
C. albicans ATCC90028 MIC > 64 μg/mL
[23]
9 - - C. neoformans ATCC9011 MIC > 64 μg/mL
C. albicans ATCC90028 MIC > 64 μg/mL
[23]
10 - - C. neoformans ATCC9011 MIC > 64 μg/mL
C. albicans ATCC90028 MIC > 64 μg/mL
[23]
11 21-Hydroxy
rustmicin
Micromonospora species UV Mutant (MA 7186) C. tropicalis MY1012 MIC = 0.024 μg/mL
C. albicans MY1055 MIC = 12.5 μg/mL
C. neoformans MY2062 MIC = 0.1 μg/mL
[22]
12 Galbonolide B Micromonospora species (MA 7094) and UV Mutant (MA 7186) C. neoformans MY2062 MIC = 12.5 μg/mL
C. tropicalis MY1012 MIC = 200 μg/mL
C. albicans MY1055 MIC > 200 μg/mL
[22]
13 21-Hydroxy
galbonolide B
Micromonospora species UV Mutant (MA 7186) C. tropicalis MY1012 MIC = 0.78 μg/mL
C. neoformans MY2062 MIC = 3.1 μg/mL
[22]
14 Preussolide A Preussia typharum C. neoformans H99 (37 °C) MIC = 4 μg/mL
C. neoformans H99 (23 °C) MIC = 8 μg/mL
C. albicans ATCC 10231 MIC = 256 μg/mL
A. fumigatus AF239 MIC = 8 μg/mL
[24]
15 Preussolide B Preussia typharum C. neoformans H99 (37 °C) MIC = 32 μg/mL
C. neoformans H99 (23 °C) MIC = 32 μg/mL
C. albicans ATCC 10231 MIC = 256 μg/mL
[24]
16 Oligomycin A
s-Trans
Streptomyces C. albicans ATCC 24433 MIC = 2–4 μg/mL
C. krusei 432M (MIC = 1–2 μg/mL)
C. parapsilosis ATCC 22019 MIC = 2 μg/mL
C. utilis 84 MIC = 1 μg/mL
C. tropicalis 3019 MIC = 1 μg/mL
A. niger MIC = 0.5–2 μg/mL
C. humicolus ATCC 9949 MIC = 2 μg/mL
T. mentagrophytes ATCC 9533 MIC = 10 μg/mL
C. albicans ATCC 14053 MIC = 4 μg/mL
A. niger ATCC 16404 MIC = 0.125 μg/mL
C. albicans ATCC 14053 MIC = 4 μg/mL
C. humicolus ATCC 9949 MIC = 2 μg/mL
A. niger ATCC 10335 MIC = 2 μg/mL
A. niger MIC = 0.125 μg/mL
[25,26,27,28,29,30,31,33]
17 Oligomycin A
s-Cis
Streptomyces C. albicans ATCC 24433 MIC = 2–4 μg/mL
C. krusei 432M MIC = 1–2 μg/mL
C. parapsilosis ATCC 22019 MIC = 2 μg/mL
C. utilis 84 MIC = 1 μg/mL
C. tropicalis 3019 MIC = 1 μg/mL
A. niger MIC = 0.5–2 μg/mL
C. humicolus ATCC 9949 (MIC = 2 μg/mL)
Aspergillus carbonarius M333 (MIC = 2 μg/mL)
A. westerdijkiae NRRL 3174 (MIC = 8 μg/mL)
A. parasiticus CBS 100926 (MIC = 4 μg/mL)
A. nidulans KE202 (MIC = 75 μg/mL)
A. niger OT304 (MIC = 4 μg/mL)
A. terreus CT290 (MIC = 75 μg/mL)
A. fumigatus CF140 (MIC = 100 μg/mL)
[25,26,27,28,29,30,32]
18 - - C. albicans ATCC 24433 (MIC > 32 μg/mL)
C. parapsilosis ATCC 22019 (MIC > 32 μg/mL)
C. krusei 432M (MIC > 32 μg/mL)
A. niger 137a (MIC > 32 μg/mL)
[26]
19 - - C. albicans ATCC 24433 (MIC > 32 μg/mL)
C. parapsilosis ATCC 22019 (MIC > 32 μg/mL)
C. krusei 432M (MIC > 32 μg/mL)
A. niger 137a (MIC > 32 μg/mL)
[26]
20 - - C. albicans ATCC 24433 (MIC > 32 μg/mL)
C. parapsilosis ATCC 22019 (MIC > 32 μg/mL)
C. krusei 432M (MIC > 32 μg/mL)
A. niger 137a (MIC > 32 μg/mL)
[26]
21 (33S)-oligomycin A - C. parapsilosis ATCC 22019 MIC = 1 μg/mL
C. albicans ATCC 24433 MIC = 4 μg/mL
C. utilis 84 MIC = 2 μg/mL
C. tropicalis 3019 MIC = 1 μg/mL
C. krusei 432 M MIC = 4 μg/mL
A. niger 137 a MIC = 2 μg/mL
[28]
22 - - C. albicans ATCC 14053 MIC = 16 μg/mL
A. niger ATCC 16404 MIC = 4 μg/mL
[31]
23 Bromo-
oligomycin A
- A. niger ATCC 16404 MIC >16 μg/mL
C. albicans ATCC 14053 MIC > 16 μg/mL
C. humicolus MIC = 2 μg/mL
[29]
24 Oligomycin E Streptomyces species strain HG29 Aspergillus carbonarius M333 (MIC = 2 μg/mL)
A. westerdijkiae NRRL 3174 (MIC = 8 μg/mL)
A. parasiticus CBS 100926 (MIC = 4 μg/mL)
A. nidulans KE202 (MIC = 75 μg/mL)
A. niger OT304 (MIC = 4 μg/mL)
A. terreus CT290 (MIC = 75 μg/mL)
A. fumigatus CF140 (MIC = 100 μg/mL)
[32]
25 Oligomycin C Streptomyces diastaticus A. niger ATCC 10335 MIC = 2 μg/mL [30]
26 - - - [33]
27 - - A. niger MIC = 2 μg/mL [33]
28 - - A. niger MIC = 2 μg/mL [33]
29 Neomaclafungin A Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 3 μg/mL [27]
30 Neomaclafungin B Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 3 μg/mL [27]
31 Neomaclafungin C Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 1 μg/mL [27]
32 Neomaclafungin D Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 1 μg/mL [27]
33 Neomaclafungin E Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 1 μg/mL [27]
34 Neomaclafungin F Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 3 μg/mL [27]
35 Neomaclafungin G Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 3 μg/mL [27]
36 Neomaclafungin H Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 3 μg/mL [27]
37 Neomaclafungin I Actinoalloteichus species NPS702 T. mentagrophytes ATCC 9533 MIC = 3 μg/mL [27]
38 Brasilinolide A Nocardia brasiliensis IFM0406 A. niger IFM 40406 MIC = 3.13 μg/mL [34]
39 Brasilinolide B Nocardia brasiliensis IFM0406 A. niger MIC = 12.5 μg/mL
A. fumigatus IFM 41219 MIC = 12.5 μg/mL
C. albicans ATCC 90028 MIC = 25 μg/mL
C. albicans IFM 40007 MIC = 12.5 μg/mL
C. albicans 94–2530 MIC = 25 μg/mL
C. krusei M 1005 MIC = 25 μg/mL
C. parapsilosis ATCC 90018 MIC = 12.5 μg/mL
C. glabrata ATCC 90030 MIC = 25 μg/mL
C. neoformans ATCC 90112 MIC = 12.5 μg/mL
C. neoformans 145 A MIC = 25 μg/mL
[35]
40 Copiamycin C. albicans Yu 1200 MIC = 25 μg/mL [36]
41 Methylcopiamycin - C. albicans Yu 1200 MIC = 25 μg/mL [36]
42 Demalonylmethylcopiamycin - C. albicans Yu 1200 MIC = 6.25 μg/mL [36]
43 Langkolide Streptomyces species Acta 3062 Candida glabrata IC50 = 1.00 ± 0.02 μM
C. albicans IC50 = 1.23 ± 0.10 μM
[37]
44 Cyphomycin Brazilian Streptomyces ISID311 A. fumigatus 11628 MIC = 0.5 μg/mL
C. glabrata 4720 MIC = 0.5 μg/mL
C. auris B11211 MIC = 4 μg/mL
[38]
45 Caniferolide A Streptomyces caniferus CA-271066 A. fumigatus ATCC46645 MIC = 2–4 μg/mL
C. albicans MY1005 MIC = 0.5–1 μg/mL
[39]
46 Caniferolide B Streptomyces caniferus CA-271066 A. fumigatus ATCC46645 MIC = 2–4 μg/mL
C. albicans MY1005 MIC = 1–2 μg/mL
[39]
47 Caniferolide C Streptomyces caniferus CA-271066 A. fumigatus ATCC46645 MIC = 4–8 μg/mL
C. albicans MY1005 MIC = 0.5–1 μg/mL
[39]
48 Caniferolide D Streptomyces caniferus CA-271066 A. fumigatus ATCC46645 MIC = 4–8 μg/mL
C. albicans MY1005 MIC = 0.5–1 μg/mL
[39]
49 Iseolide A Streptomyces species DC4-5 C. albicans NBRC0197 MIC = 0.39 μg/mL [40]
50 Iseolide B Streptomyces species DC4-5 C. albicans NBRC0197 MIC = 6.25 μg/mL [40]
51 Iseolide C Streptomyces species DC4-5 C. albicans NBRC0197 MIC = 3.16 μg/mL [40]
52 Astolide A Streptomyces hygroscopicus C. albicans ATCC 14053 (MIC = 2.5 μg/mL)
A. niger ATCC 16404 (MIC = 1.25 μg/mL)
C. albicans 1582 (MIC = 2.53 μg/mL)
C. tropicales 1402 (MIC = 5.06 μg/mL)
A. niger 219 (MIC = 2.53 μg/mL)
[41]
53 Astolide B Streptomyces hygroscopicus C. albicans ATCC 14053 (MIC = 1.25 μg/mL)
A. niger ATCC 16404 (MIC = 0.6 μg/mL)
C. albicans 1582 (MIC = 2.51 μg/mL)
C. tropicales 1402 (MIC = 5.01 μg/mL)
A. niger 219 (MIC = 2.51 μg/mL)
[41]
54 Guanidylfungin A Streptomyces hygroscopicus No. 662 C. albicans IAM 4888 MIC = 12.5 μg/mL
C. albicans Yu 1200 MIC = 50 μg/mL
A. fumigatus IAM 2153 MIC = 25 μg/mL
[36,42]
55 Methylguanidylfungin A - C. albicans IAM 4888 MIC = 25 μg/mL
C. albicans Yu 1200 MIC = 50 μg/mL
A. fumigatus IAM 2153 MIC = 12.5 μg/mL
[36]
56 Ethyl-
guanidylfungin A
- C. albicans IAM 4888 MIC = 25 μg/mL
A. fumigatus IAM 2153 MIC = 25 μg/mL
[36]
57 Butyl-
guanidylfungin A
- C. albicans IAM 4888 MIC = 25 μg/mL
A. fumigatus IAM 2153 MIC = 50 μg/mL
[36]
58 Allyl-
guanidylfungin A
- C. albicans IAM 4888 MIC = 25 μg/mL
A. fumigatus IAM 2153 MIC = 25 μg/mL
[36]
59 - - C. albicans IAM 4888 MIC = 3.12 μg/mL
C. albicans Yu 1200 MIC = 6.25 μg/mL
A. fumigatus IAM 2153 MIC = 3.12 μg/mL
[36]
60 - - C. albicans IAM 4888 MIC > 100 μg/mL
C. albicans Yu 1200 MIC > 100 μg/mL
A. fumigatus IAM 2153 MIC = 50 μg/mL
[36]
61 - - C. albicans IAM 4888 MIC = 100 μg/mL
C. albicans Yu 1200 MIC = 100 μg/mL
A. fumigatus IAM 2153 MIC = 12.5 μg/mL
[36]
62 Amphotericin B Streptomyces nodosus C. neoformans, Candida species, and A. fumigatus [7,8]
Polyether
polyketides
63 Amphidinol 3 dinoflagellate Amphidinium klebsii A. niger MEC = 8 μg/disk [52,53]
64 - - A. niger MEC = 20 μg/disk [52]
65 - - - [52]
66 Amphidinol 18 Dinoflagellate Amphidinium carterae C. albicans MIC = 9 μg/mL [54]
67 Amphidinol A dinoflagellate Amphidinium carterae C. albicans MIC = 19 μg/mL [51]
68 Karatungiol A marine dinoflagellates A. niger [55]
69 Amphidinol 6 dinoflagellate Amphidinium klebsii A. niger MEC = 6 μg/disk [53]
70 Amphidinol 2 dinoflagellate Amphidinium klebsii A. niger MEC = 6 μg/disk [53]
71 Amphidinol 7 dinoflagellate Amphidinium klebsii A. niger MEC = 10 μg/disk [53]
72 Desulfurization amphidinol 7 - A. niger MEC = 8 μg/disk [53]
73 Amphidinol 20 dinoflagellate Amphidinium carterae A. niger [56]
74 Amphidinol 21 dinoflagellate Amphidinium carterae A. niger [56]
75 Carteraol E marine dinoflagellates A. niger MEC = 15 μg/disk [57]
76 Yessotoxin dinoflagellate Protoceratium reticulatum A. niger [58]
77 Desulfated
yessotoxin
- A. niger [58]
78 Hydrogen-desufated
yessotoxin
- A. niger [58]
79 Forazoline A Actinomadura species strain WMMB-499 C. albicans K1 MIC = 16 μg/mL [60].
Xanthone
polyketides
80 Albofungin Actinomyces tumemacerans
strain INMI P-42
C. albicans, Candida guiliermondii, Candida hrusei, Candida parahrusei, C. tropicalis, Candida stellatoidea, C. neoformans, A. niger, Aspergillus oryzae, and Saccharomyces cerevisiae
MICs = 0.0075–1 μg/mL
[65]
81 Sch 42137 Actinoplane species SCC 1906 C. albicans, C. tropicalis, C. stellatoidea,
and C. parapsilosis
MICs = 0.125 µg/mL
[66]
82 Sch 54445 Actinoplane species SCC 2314
and ATCC 55600
C. albicans, C. tropicalis, C. stellatoidea,
and C. parapsilosis
MICs = 0.00038 µg/mL
[67]
83 Sch 56036 Actinoplanes species (SCC 2314, ATCC 55600) C. albicans and C. tropicalis MICs = 0.017 μg/mL [68]
84 15R-17,18-dehydroxantholipin mangrove Streptomyces qinglanensis 172205 C. albicans MIC = 3.13 μg/mL [69]
85 Turbinmicin bacterium Micromonospora species WMMC-415 C. albicans, C. glabrata, C. tropicalis, C. auris, A. fumigatus, Fusarium and Scedosporium species
MICs = 0.03–0.5 µg/mL
[70]
86 Parnafungin A1 Fusarium larvarum various Candida species [73]
87 Parnafungin B1 Fusarium larvarum various Candida species [73]
88 Parnafungin A2 Fusarium larvarum various Candida species [73]
89 Parnafungin B2 Fusarium larvarum various Candida species [73]
90 - - - [73]
91 - - - [73]
92 Parnafungin C Fusarium larvarum strain F-155,597 C. albicans, C. lusitaniae, C. krusei, and C. tropicalis
MICs = 0.08–2.5 μg/mL
[76]
93 Parnafungin D Fusarium larvarum strain F-155,597 C. albicans, C. glabrata, C. parapsilosis, C. lusitaniae, C. krusei, and C. tropicalis
MICs = 0.016–5 μg/mL
[76]
Linear
polyketides
94 Khafrefungin endophytic fungi C. albicans MIC = 2 μg/mL
C. neoformans MIC = 2 μg/mL
S. cerevisiae MIC = 15.6 μg/mL
[78]
95 - - S. cerevisiae MIC > 200 µM [79]
96 - - - [79]
97 - - - [79]
98 - - S. cerevisiae MIC = ~10 µM [80]
99 Basiliskamide A Bacillus laterosporus PNG 276 C. albicans MIC = 1 μg/mL
A. fumigatus MIC = 2.5 μg/mL
[81]
100 Basiliskamide B Bacillus laterosporus PNG 276 C. albicans MIC = 3.1 μg/mL
A. fumigatus MIC = 5 μg/mL
[81]
101 YM-45722 - C. albicans MIC = 25 μg/mL
A. fumigatus MIC > 50 μg/mL
[81]
Hybrid polyketide nonribosomal peptides 102 Pneumocandin B0 fungus Glarea lozoyensis Candida and Aspergillus species [87,88]
103 caspofungin - Candida and Aspergillus species [84]
104 Burkholdine 1229 bacteria Burkholderia ambifaria 2.2N S. cerevisiae MIC = 0.4 μg/mL
C. albicans MIC = 12.5 μg/mL
A. niger MIC = 12.5 μg/mL
[89]
105 Burkholdine 1097 bacteria Burkholderia ambifaria 2.2N S. cerevisiae MIC = 1.6 μg/mL
A. niger MIC = 1.6 μg/mL
C. albicans MIC = 12.5 μg/mL
[89]
106 Burkholdine 1215 bacteria Burkholderia ambifaria S. cerevisiae MIC = 0.15 μg/mL
C. albicans MIC = 0.15 μg/mL
A. niger MIC = 0.15 μg/mL
[90]
107 Burkholdine 1119 bacteria Burkholderia ambifaria S. cerevisiae MIC = 0.1 μg/mL
C. albicans MIC = 0.4 μg/mL
A. niger MIC = 0.1 μg/mL
[90]
108 Burkholdine 1213 bacteria Burkholderia ambifaria S. cerevisiae MIC = 2.0 μg/mL
C. albicans MIC = 31.0 μg/mL
A. niger MIC = 2.0 μg/mL
[90]
Pyridine
derivatives
109 Funiculosin Penicillium funiculosum THOM C. albicans (MIC = 2 µg/mL)
C. utilis (MIC = 5 µg/mL)
C. neoformans (MIC = 2 µg/mL)
S. cerevisiae (MIC = 20 µg/mL)
T. mentagrophytes (MIC = 15 µg/mL)
T. rubrun (MIC = 3.9 µg/mL)
M. gypseum (MIC < 0.12 µg/mL)
B. derniatitidis (MIC < 0.12 µg/mL)
H. pedrosoi (MIC = 15 µg/mL)
[91,94]
Other
polyketides
110 Emodin fungus Talaromyces species ZH-154 C. albicans ATCC 10231 MIC = 6.25 μg/mL
A. niger ATCC 13496 MIC = 12.5 μg/mL
[95]
111 Dkyrin fungus Talaromyces species ZH-154 C. albicans ATCC 10231 MIC = 12.5 μg/mL [95]
112 Hippolachnin A sponge Hippospongia lachne C. neoformans MIC = 0.41 μM [96]
113 Wortmannin Fusarium oxysporum N17B C. albicans MIC = 0.78 μg/mL [97]
114 Microketide A fungus Microsphaeropsis species RA10-14 C. albicans, C. truncatum,
G. musarum, and P. calabae
MICs = 1.56–3.13 μg/mL
[99]
115 Microketide B fungus Microsphaeropsis species RA10-14 C. albicans, C. truncatum,
G. musarum, and P. calabae
MICs = 1.56–3.13 μg/mL
[99]
116 Macrotermycin A Amycolatopsis species M39 C. albicans ATCC 10231 MIC = 10 μg/mL
S. cerevisiae ATCC9763 MIC = 5 μg/mL
[100]
117 Macrotermycin C Amycolatopsis species M39 C. albicans ATCC 10231 MIC = 25 μg/mL
S. cerevisiae ATCC9763 MIC = 20 μg/mL
[100]
118 F2928-1 fungus Hypomyces pseudocorticiicola
FKA-73
A. fumigatus IFM 61493 MIC = 32 μg/mL
A. fumigatus IFM 62104 MIC = 32 μg/mL
A. udagawae IFM 62100 MIC = 32 μg/mL
A. felis IFM 62093 MIC = 64 μg/mL
A. lentulus IFM 62073 MIC = 64 μg/mL
C. auris IFM 64524 MIC = 2 μg/mL
C. auris IFM 65059 MIC = 2 μg/mL
C. auris IFM 65061 MIC = 2 μg/mL
[101]
119 Hakuhybotrol fungus Hypomyces pseudocorticiicola
FKA-73
A. fumigatus IFM 61493 MIC > 128 μg/mL
A. fumigatus IFM 62104 MIC > 128 μg/mL
A. udagawae IFM 62100 MIC > 128 μg/mL
A. felis IFM 62093 MIC > 128 μg/mL
A. lentulus IFM 62073 MIC > 128 μg/mL
C. auris IFM 64524 MIC > 128 μg/mL
C. auris IFM 65059 MIC > 128 μg/mL
C. auris IFM 65061 MIC > 128 μg/mL
[101]
120 Cladobotric acid A fungus Hypomyces pseudocorticiicola
FKA-73
A. fumigatus IFM 61493 MIC = 32 μg/mL
A. fumigatus IFM 62104 MIC = 32 μg/mL
A. udagawae IFM 62100 MIC = 32 μg/mL
A. felis IFM 62093 MIC = 128 μg/mL
A. lentulus IFM 62073 MIC = 64 μg/mL
C. auris IFM 64524 MIC = 4 μg/mL
C. auris IFM 65059 MIC = 8 μg/mL
C. auris IFM 65061 MIC = 8 μg/mL
[101]
121 Cladobotric acid F fungus Hypomyces pseudocorticiicola
FKA-73
A. fumigatus IFM 61493 MIC > 128 μg/mL
A. fumigatus IFM 62104 MIC > 128 μg/mL
A. udagawae IFM 62100 MIC > 128 μg/mL
A. felis IFM 62093 MIC > 128 μg/mL
A. lentulus IFM 62073 MIC > 128 μg/mL
C. auris IFM 64524 MIC > 128 μg/mL
C. auris IFM 65059 MIC > 128 μg/mL
C. auris IFM 65061 MIC > 128 μg/mL
[101]
122 Cladobotric acid E fungus Hypomyces pseudocorticiicola
FKA-73
A. fumigatus IFM 61493 MIC = 8 μg/mL
A. fumigatus IFM 62104 MIC = 16 μg/mL
A. udagawae IFM 62100 MIC = 32 μg/mL
A. felis IFM 62093 MIC = 64 μg/mL
A. lentulus IFM 62073 MIC = 32 μg/mL
C. auris IFM 64524 MIC = 4 μg/mL
C. auris IFM 65059 MIC = 2 μg/mL
C. auris IFM 65061 MIC = 2 μg/mL
[101]
123 Cladobotric acid H fungus Hypomyces pseudocorticiicola
FKA-73
A. fumigatus IFM 61493 MIC = 32 μg/mL
A. fumigatus IFM 62104 MIC = 32 μg/mL
A. udagawae IFM 62100 MIC = 64 μg/mL
A. felis IFM 62093 MIC = 64 μg/mL
A. lentulus IFM 62073 MIC = 64 μg/mL
C. auris IFM 64524 MIC = 16 μg/mL
C. auris IFM 65059 MIC = 16 μg/mL
C. auris IFM 65061 MIC = 32 μg/mL
[101]
124 Pyrenulic acid A fungus Hypomyces pseudocorticiicola
FKA-73
A. fumigatus IFM 61493 MIC = 32 μg/mL
A. fumigatus IFM 62104 MIC = 32 μg/mL
A. udagawae IFM 62100 MIC = 32 μg/mL
A. felis IFM 62093 MIC > 128 μg/mL
A. lentulus IFM 62073 MIC > 128 μg/mL
C. auris IFM 64524 MIC = 16 μg/mL
C. auris IFM 65059 MIC = 16 μg/mL
C. auris IFM 65061 MIC = 16 μg/mL
[101]
125 Campafungin A Plenodomus enteroleucus Strain F-146,176 C. neoformans H77 MIC = 8 μg/mL [102]
126 Campafungin B Plenodomus enteroleucus Strain F-146,176 C. neoformans H77 MIC = 4 μg/mL [102]
127 Campafungin C Plenodomus enteroleucus Strain F-146,176 C. neoformans H77 MIC = 4 μg/mL [102]
128 Campafungin D Plenodomus enteroleucus Strain F-146,176 C. neoformans H77 MIC = 8 μg/mL [102]