Figure 4.

Results of CCR8 gene expression profiling. (a) The differential expression of CCR8 between tumor tissues and adjacent normal tissues, categorized by cancer type. The distribution of gene expression levels is depicted using a box plot, with the red box plot representing tumor tissue and the blue one representing normal tissue. The statistical significance computed by the Wilcoxon test is annotated by the number of stars (**: p-value <0.01; ***: p-value <0.001). (b) Overall CCR8 protein expression across 44 organs in normal tissues. (c) Results of evaluating CCR8 expression in immune cells infiltrating the tumor microenvironment.