Table 2.
Risk and survival analyses before matching and when matched for age and gender.
| Variable(s) Matched | n | Patients with AD | Risk | Risk Difference (p-Value) |
Risk Ratio (95% CI) |
Kaplan–Meier Survivability (%) |
p-Value (Log-Rank Test) |
Hazard Ratio (95% CI) |
p-Value |
|---|---|---|---|---|---|---|---|---|---|
| None | p < 0.001 * | p < 0.001 * | |||||||
| Cohort 1 | 31,418,814 | 179,136 | 0.006 | 0.008 | 2.363 | 98.89% | 1.868 | ||
| Cohort 2 | 1,232,751 | 16,609 | 0.013 | (p < 0.001 *) | (2.326, 2.401) | 98.00% | (1.838, 1.898) | ||
| Age only | p < 0.001 * | p < 0.001 * | |||||||
| Cohort 1 | 1,233,771 | 6864 | 0.006 | 0.008 | 2.489 | 98.92% | 1.975 | ||
| Cohort 2 | 1,233,771 | 17,083 | 0.014 | (p < 0.001 *) | (2.420, 2.559) | 97.95% | (1.921, 2.032) | ||
| Gender only | p < 0.001 * | p < 0.001 * | |||||||
| Cohort 1 | 1,221,975 | 7235 | 0.006 | 0.008 | 2.318 | 98.85% | 1.834 | ||
| Cohort 2 | 1,221,975 | 16,774 | 0.014 | (p < 0.001 *) | (2.256, 2.383) | 97.96% | (1.784, 1.885) | ||
| Age and gender | p < 0.001 * | p < 0.001 * | |||||||
| Cohort 1 | 1,231,244 | 6784 | 0.006 | 0.008 | 2.508 | 98.94% | 1.995 | ||
| Cohort 2 | 1,231,244 | 17,017 | 0.014 | (p < 0.001 *) | (2.439, 2.580) | 97.96% | (1.939, 2.052) |
Cohort 1 represents the “normal oral health” cohort, while Cohort 2 represents the “poor oral health” cohort. Propensity score matching was performed to match for age and gender. Statistically significant risks or survival probabilities are indicated by an asterisk. Abbreviations—AD: Alzheimer’s disease, 95% CI: 95% confidence interval.