Comparison of trajectories generated by synchronous and asynchronous update modes derived from the APT model described in Figure 6. (a) In the synchronous update mode, all valid transitions are fired simultaneously. For instance, in the state, rules R1, R2 and R3 are satisfied (see Figure 6b for rule definitions) and are thus executed simultaneously. The resulting dynamics are thus deterministic and necessarily end up in the empty state ∅. (b) In contrast, the asynchronous update mode used in EDEN opens an alternative trajectory from the state by separately firing, on the one hand R2 or R3, and on the other hand R1, possibly leading to the alternative stable state observed in [107] experiments.