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Protein therapeutics.
| Drug | Target/Mechanism | Experimental System | Further Development? | Ref. |
|---|---|---|---|---|
| METRNL | Enhances myogenesis | (1) BaCl2 TA muscle injury model (2) Aged male C57BL/6J mice (24–26 mo) |
Not assessed in aged mice without injury | [127] |
| GDF11PRO-Fc | GDF11 and myostatin inhibitor | (1) Adult male mice the (2) mdx model of Duchenne muscular dystrophy | Not assessed in aged mice | [132] |
