Table 3.
Disposal of unused reproductive material as part of fertility preservation in cancer patients.
| Author/Year (Type of Study) |
Number of Patients Who Cryopreserved Material | Reproductive Material | Disposal of Unused Cryopreserved Material | Usage Rate | |
|---|---|---|---|---|---|
| Decision | Result | ||||
| Ferrari 2016 (SR) [45] | 4291 | Sperm | Discard | 16% | 8.3% |
| Sankara-Narayana 2019 (PR) [43] | 2717 * | Sperm | Discard due to retained/recovered fertility or sperm production | 35.9% | 7% |
| Lost to follow-up | 30.8% | ||||
| Discard due to death | 26.3% | ||||
| Moravek 2018 (PR) [36] | 204 | Oocytes and embryos | Ongoing storage | 34.3% | 10.3% |
| Donate to research | 33.8% | ||||
| Donate to another couple or family member | 24.5% | ||||
| Discard | 7.4% | ||||
| Muller 2016 (PR) # [46] | 898 | Sperm | Ongoing storage | 55.4% | 10.7% |
| Discard upon request (death, retained/recovered fertility, spontaneous pregnancy, no desire to have children) |
33.9% | ||||
| Johnson 2013 (PR) # [50] | 423 | Sperm | Ongoing storage | 42.8% | 8.5% |
| Electively discarded | 30.5% | ||||
| Failed to bank a sample | 10.6% | ||||
| Discard due to death | 7.6% | ||||
* 2717 men including 2085 cancer patients, 234 non-cancer patients, and 398 healthy men in the control group. #—reference study from included studies in this review; PR—primary research; SR—systematic review.