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Association between eccDNA frequency and the RNA expression level. (A). RNAseq reads (upper panel), protein coding genes (middle panel) were grouped into bins of 1-Mb step-wise across chromosome 22. EccDNAs clustering patterns (lower panel) were similar to those of RNAseq reads and protein-coding gene patterns across all samples. (B). Relations of the eccDNA counts and the average transcription level of the five indicated (#22, 24, 77, 80, 83) samples.
