Table 3.
Nominal dose statistics for manual flash (MF) and robust optimized (RO) plans.
| Parameter | MF Plan | RO Plan | p-Value | |
|---|---|---|---|---|
| Target volume | CTV V95% (%) | 99.61 ± 0.07 | 97.67 ± 0.21 | <0.001 * |
| CTV V100% (%) | 97.45 ± 0.25 | 92.51 ± 0.43 | <0.001 * | |
| CTV V107% (%) | 5.35 ± 0.70 | 4.08 ± 0.33 | 0.105 | |
| CTV D98% (cGy) | 4995.00 ± 6.41 | 4466.62 ± 101.17 | <0.001 * | |
| CTV D2% (cGy) | 5382.38 ± 5.83 | 5377.06 ± 4.39 | 0.484 | |
| CTV Dmax (cGy) | 5509.03 ± 10.64 | 5523.94 ± 10.79 | 0.326 | |
| Organs at risk | Ipsilateral lung V500cGy (%) | 60.64 ± 0.56 | 60.97 ± 1.01 | 0.809 |
| Ipsilateral lung V1000cGy (%) | 44.44 ± 0.44 | 44.50 ± 0.44 | 0.921 | |
| Ipsilateral lung V2000cGy (%) | 30.02 ± 0.42 | 29.78 ± 0.71 | 0.768 | |
| Contralateral lung V500cGy (%) | 9.58 ± 0.33 | 8.08 ± 0.42 | 0.002 * | |
| Heart Dmean (cGy) | 370.00 ± 12.58 | 345.76 ± 10.85 | 0.114 |
Figures are expressed in mean ± standard deviation. CTV, clinical target volume; D2%/98%, dose received by 2%/98% of structure, respectively; Dmax, maximum dose received by structure; Dmean, average dose received by structure; V95%/100%/107%, volume of structure receiving more than 95%/100%/107% of prescribed dose, respectively; V500/1000/2000cGy, volume of structure receiving 500/1000/2000 cGy dose, respectively. * denotes statistically significant difference.