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General scheme of ChE modifier. X—enzyme modifier; E—ChE; ES—complex of ChE with substrate; Kx—equilibrium dissociation constant for activator binding to free ChE; Ks—equilibrium dissociation constant for substrate binding to free ChE; kcat—rate for the product-generating chemical step; α—value determining the relative affinity for X binding to free ChE; β—factor determining the overall rate enhancement induced by the modifier.
