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. 2023 Nov 10;24(22):16181. doi: 10.3390/ijms242216181

Figure 3.

Figure 3

RT-PCR analysis of gingival fibroblasts in the presence of SB431542. RT-PCR analysis of gingival fibroblasts incubated with acid lysates of bone allograft (ALBA) with and without the TGF-β RI kinase inhibitor SB431542. Expression analysis showed that the blocking of TGF-β signaling reduced ALBA-induced expression of IL11, AREG, and C11orf96 in gingival fibroblasts. Data points represent four independent experiments. Data were normalized against untreated control cells with x-fold changes compared to the untreated cells. The analysis was based on a paired t-test.