Figure 6.

Phase 2 context fear conditioning in female mice, separated by swim condition. Female wild types are represented by teal solid lines, and female heterozygotes are represented by blue dashed lines. Fear conditioning occurred 4 weeks after swim stress exposure for Phase 2. Mice were trained on Day 0 in Context A (A,C). Two days later (Day 2), mice were placed back in Context A to test for context fear expression (B,D). Data were analyzed within each training/testing stage and within each sex, using 3-way repeated-measures ANOVAs (time × PMAT genotype × swim condition) and pairwise comparisons with Bonferroni correction. Data are percent time spent freezing for each 30 s period following the foot shock (A,C) or every 30 s of testing (B,D). Data are graphed as mean ± 95% confidence interval.