2-FDG |
2-[18F]fluoro-2-deoxy-D-glucose (substrate for GLUTs) |
2-hPG |
2-h post-load glucose |
11C-PiB |
[11C]-labeled Pittsburgh compound B (marker for amyloid beta accumulation) |
AB |
amyloid-beta |
ABPP |
amyloid beta precursor protein |
AD |
Alzheimer’s disease |
AGE |
advanced glycation end product |
AMG |
[14C]α-methyl D-glucopyranoside |
AS160 |
AKT substrate 160 |
BAD |
Bcl2-associated agonist of cell death |
BBB |
blood–brain barrier |
BBMEC |
bovine brain microvascular endothelial cell |
BGU |
brain glucose utilization |
CA4 |
cornu ammonis 4 area |
CSF |
cerebrospinal fluid |
CNS |
central nervous system |
CREB/ICER |
CRE-binding proteins |
DHA |
dihydroxyacetone |
DM |
diabetes mellitus |
FOXO1 |
forkhead box protein O1 |
GA |
glycated albumin |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
GLUT1–GLUT8 |
glucose transporter type 1–8 proteins |
GSK3B |
glycogen synthase kinase 3 beta |
HbA1c |
glycated hemoglobin A1c |
hCMEC/D3 |
human cerebral microvascular endothelial cell line/D3 |
HOMA-IR |
homeostatic model assessment for insulin resistance |
IGF1 |
insulin-like growth factor 1 |
IL6 |
interleukin 6 |
IR |
insulin resistance |
JAK |
janus kinase |
MAPT |
microtubule associated protein tau gene (human) |
Me-4FDG |
α-methyl-4-[18F]fluoro-4-deoxy-D-glucopyranoside (substrate for SGLTs) |
MGO |
methylglyoxal |
MRI |
magnetic resonance imaging |
NFKB-p65 |
nuclear factor NF-kappa-B subunit p65 |
OGTT |
oral glucose tolerance test |
PET |
positron emission tomography |
PI3K |
phosphatidylinositol 3-kinase |
PIP3 |
phosphatidylinositol 3,4,5-trisphosphate |
PKB |
protein kinase B (alias AKT) |
PM |
plasma membrane |
pO2 |
partial pressure of oxygen |
RAGE |
advanced glycation end product receptor |
ROS |
reactive oxygen species |
S100-B |
S100 calcium-binding protein B |
S100b |
S100b gene (mouse) |
SGLT1–2 |
sodium/glucose cotransporter types 1–2 |
Slc2a1–8 |
solute carrier family 2 members 1–8 genes (mouse) |
SLC2A1–8 |
solute carrier family 2 members 1–8 genes (human) |
Slc5a1–2 |
solute carrier family 5 members 1–2 genes (mouse) |
SLC5A1–2 |
solute carrier family 5 members 1–2 genes (human) |
STAT |
signal transducer and activator of transcription |
SVD |
small vessel disease |
TD1 |
type 1 diabetes mellitus |
T2D |
type 2 diabetes mellitus |
TBI |
traumatic brain injury |
TNF |
tumor necrosis factor |
VD |
vascular dementia |