Table 1.

A summary of the docking results for Dapagliflozin on CDK1/PBK/CHEK1 oncogenic signature. The results comprise the binding energies, binding distances, the interacting amino acid on the receptor, and the type of bond for each ligand–receptor interaction.

Oncogenes and Binding Energy []	Interacting Amino Acids and Binding Distance ()	Interaction Type
CDK1 [ΔG = −8.4 kcal/mol]	GLN132 (1.94 Å, 2.72 Å)	Conventional Hydrogen Bond
	ALA145	Alkyl
	ALA132, LEU135, PHE82, VAL18	Pi–Alkyl
	PHE82	Pi–Sigma
PBK [ΔG = −7.2 kcal/mol]	ASN45 (2.81 Å), ARG278 (2.96 Å), THR24 (3.07 Å)	Conventional Hydrogen Bond
	PRO280	Alkyl and Pi–Alkyl bonds
	THR277	Carbon Hydrogen Bond
	TYR47	Pi-Pi-T shaped and Pi-Pi Stacked
CHEK1 [ΔG = −8.3 kcal/mol]	ASP148 (2.37 Å)	Conventional Hydrogen Bond
	VAL68, LEU15, LEU84	Alkyl
	LEU137, ALA36, VAL23	Pi–Alkyl
	GLY90	Carbon Hydrogen Bond
	LEU15	Pi–Sigma
	SER147	Pi–Donor Hydrogen bond