Table 2. AEs of COVID-19 vaccine after the first and second doses.
Bowker’s test (equivalent to the McNemar test) was performed for statistical analyses.
AEs = adverse events
| Medical characteristics (n = 922) | Frequency of AEs, N (%) | P-value | |
| First dose | Second dose | ||
| Signs and symptoms (AEs) | |||
| Asymptomatic | 255 (27.66) | 436 (47.29) | <0.0001 |
| Symptomatic | 667 (72.34) | 486 (52.71) | |
| Fever | |||
| No | 659 (71.48) | 728 (78.96) | <0.0001 |
| Yes | 263 (28.52) | 194 (21.04) | |
| Fatigue | |||
| No | 689 (74.73) | 822 (89.15) | <0.0001 |
| Yes | 233 (25.27) | 100 (10.85) | |
| Headache | |||
| No | 693 (75.16) | 767 (b3.38) | <0.0001 |
| Yes | 229 (24.84) | 154 (16.72) | |
| Myalgia | |||
| No | 670 (72.67) | 919 (88.83) | <0.0001 |
| Yes | 252 (27.33) | 103 (11.17) | |
| Chills | |||
| No | 882 (95.66) | 906 (98.27) | 0.0007 |
| Yes | 40 (4.34) | 16 (1.73) | |
| Nausea | |||
| No | 913 (99.02) | 916 (99.35) | 0.4053 |
| Yes | 9 (0.98) | 6 (0.65) | |
| Cough | |||
| No | 909 (98.59) | 917 (99.47) | 0.0290 |
| Yes | 13 (1.41) | 5 (0.54) | |
| Shortness of Breath | |||
| No | 921 (99.89) | 921 (99.89) | 1.000 |
| Yes | 1 (0.11) | 1 (0.11) | |
| Loss of taste and smell | |||
| No | 921 | 918 (99.57) | 0.1797 |
| Yes | 1 (0.11) | 4 (0.43) | |
| Injection-site pain | |||
| No | 661 (71.69) | 663 (71.91) | 0.8208 |
| Yes | 261 (28.31) | 259 (28.09) | |
| Duration of AEs | |||
| None | 255 (27.66) | 436 (47.29) | <0.0001 |
| Less than 24 hours | 109 (11.82) | 148 (16.05) | |
| 24–48 hours | 504 (54.66) | 284 (30.80) | |
| More than 24 hours | 54 (5.86) | 54 (5.86) | |
| Number of AEs | |||
| None | 255 (27.66) | 436 (47.29) | <0.0001 |
| 1–3 | 604 (65.51) | 468 (50.76) | |
| >3 | 63 (6.83) | 18 (1.95) | |
| Mean of AEs | 1.37 (1.24) 0–6 | 1.79 (0.85) 1–5 | |
| Severity of AEs | |||
| No AEs | 255 (27.66) | 436 (47.29) | 0.0034 |
| Mild | 469 (50.87) | 296 (32.10) | |
| Moderate | 117 (12.69) | 113 (12.26) | |
| Severe | 81 (8.79) | 77 (8.35) | |