ACAN |
aggrecan |
ACLT |
Anterior Cruciate Ligament Transection |
ADAMTS 4,5 |
A Disintegrin and Metalloproteinase with Thrombospondin motifs |
Akt |
Protein kinase B |
AMPKα |
AMP-activated protein kinase alpha |
BMP |
Bone morphogenetic protein |
CCL-27 |
C-C motif chemokine ligand 27 |
CD |
Cluster of differentiation |
cGAS |
Cyclic GMP-AMP |
COL10A1 |
Collagen type X alpha chain 1 |
COL2A1 |
Collagen type II alpha chain 1 |
CXCL8 |
CXC motif chemokine ligand 8 |
DMEM |
Dulbecco’s Modified Eagle Medium |
FADH2 |
Flavin-adenine dinucleotide, reduced |
FRZB |
Frizzled-related protein |
G-6-P DH |
Glucose 6-phosphate dehydrogenase |
GADD45 |
Growth arrest and DNA damage inducible 45 |
GLUT-1 |
Glucose transporter 1 |
GROα |
Chemokine C-X-C motif ligand 1 |
GSK3 |
Glycogen synthase kinase 3 |
HDAC |
Histone deacetylase |
HIF1α, 2α |
Hypoxia inducible factor 1α, 2α |
HK |
Hexokinase |
HMGB2 |
High-mobility group protein 2 |
IGFBP7 |
Insulin-like growth factor (IGF)-binding protein |
IHH |
Indian hedgehog |
IKK |
Inhibitory-kB kinase |
IL |
Interleukin |
JNK |
Jun N-terminal kinase |
LATS 1 |
Large tumor suppressor kinase 1 |
Lcn2 |
Lipocalin 2 |
LDH |
Lactate dehydrogenase |
LPS |
Lipopolysaccharide |
MAPK |
Mitogen activated protein kinase |
MCP-1 |
monocyte chemoattractant protein-1 |
miR |
micro RNA |
MMP |
Matrix metalloproteinase |
MOB1A/B |
Mps one binder kinase activator 1 A/B |
mPGES-1 |
Microsomal prostaglandin E synthase 1 |
MST1/2 |
Mammalian sterile 20-like kinase 1/2 |
mTORc |
Mammalian target of rapamycin complex 1 |
NADH+ |
Nicotinamide-adenine dinucleotide, reduced |
NADPH+ |
Nicotinamide-adenine dinucleotide phosphate, reduced |
NDRG2 |
NMYC downstream-regulated gene 2 |
NFkB |
Nuclear factor kappa B |
NLRP3 |
NLR family pyrin domain containing 3 |
NO |
Nitrogen monoxide |
Nrf2 |
Nuclear factor erythroid 2-related factor 2 |
OARSI |
Osteoarthritis Research Society International |
OXPHOS |
Oxidative phosphorylation |
PAI-1 |
Plasminogen activator inhibitor-1 |
PGC1α |
Peroxisome proliferator-activated receptor-gamma coactivator |
PI3K |
Phospho-inositole 3-kinase |
PKM2 |
Piruvate kinase M2 |
PPAR |
Peroxisome Proliferator-Activated Recpetor |
PTHrP |
Parathormone-related peptide |
RAGE |
Receptor of end-glycation products |
RANKL |
Receptor activator for nuclear factor kappa B ligand |
ROS |
Reactive oxygen species |
RunX2 |
Runt-related transcription factor 2 |
SASP |
Senescence-associated secretory pattern |
SAV |
Salvador |
SIRT 1,6 |
Sirtuin 1,6 |
SMAD |
Suppressor of mothers against Decapentaplegic |
Sox-9 |
Sex-determining region Y-type (SRY) high mobility group (HMG) box family of DNA binding protein 9 |
STING |
Stimulator of interferon genes |
TAZ |
Transcriptional coactivator with PDZ-binding motif |
TCA |
Tricarboxylic acid cycle |
TGF-β |
Transforming growth factor beta |
TIMP-1 |
Tissue inhibitor of metalloproteinases 1 |
TLR-4 |
Toll-like Receptor 4 |
TNF-α |
Tumor necrosis factor alpha |
TRPV4 |
Transient Receptor Potential Vanilloid 4 |
TSPYL2 |
Testis-specific Y-encoded-like protein 2 |
VEGF |
Vascular endothelial growth factor |
YAP |
Yes-associated protein |