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. 2023 Nov 17;24(22):16468. doi: 10.3390/ijms242216468
ACAN aggrecan
ACLT Anterior Cruciate Ligament Transection
ADAMTS 4,5 A Disintegrin and Metalloproteinase with Thrombospondin motifs
Akt Protein kinase B
AMPKα AMP-activated protein kinase alpha
BMP Bone morphogenetic protein
CCL-27 C-C motif chemokine ligand 27
CD Cluster of differentiation
cGAS Cyclic GMP-AMP
COL10A1 Collagen type X alpha chain 1
COL2A1 Collagen type II alpha chain 1
CXCL8 CXC motif chemokine ligand 8
DMEM Dulbecco’s Modified Eagle Medium
FADH2 Flavin-adenine dinucleotide, reduced
FRZB Frizzled-related protein
G-6-P DH Glucose 6-phosphate dehydrogenase
GADD45 Growth arrest and DNA damage inducible 45
GLUT-1 Glucose transporter 1
GROα Chemokine C-X-C motif ligand 1
GSK3 Glycogen synthase kinase 3
HDAC Histone deacetylase
HIF1α, 2α Hypoxia inducible factor 1α, 2α
HK Hexokinase
HMGB2 High-mobility group protein 2
IGFBP7 Insulin-like growth factor (IGF)-binding protein
IHH Indian hedgehog
IKK Inhibitory-kB kinase
IL Interleukin
JNK Jun N-terminal kinase
LATS 1 Large tumor suppressor kinase 1
Lcn2 Lipocalin 2
LDH Lactate dehydrogenase
LPS Lipopolysaccharide
MAPK Mitogen activated protein kinase
MCP-1 monocyte chemoattractant protein-1
miR micro RNA
MMP Matrix metalloproteinase
MOB1A/B Mps one binder kinase activator 1 A/B
mPGES-1 Microsomal prostaglandin E synthase 1
MST1/2 Mammalian sterile 20-like kinase 1/2
mTORc Mammalian target of rapamycin complex 1
NADH+ Nicotinamide-adenine dinucleotide, reduced
NADPH+ Nicotinamide-adenine dinucleotide phosphate, reduced
NDRG2 NMYC downstream-regulated gene 2
NFkB Nuclear factor kappa B
NLRP3 NLR family pyrin domain containing 3
NO Nitrogen monoxide
Nrf2 Nuclear factor erythroid 2-related factor 2
OARSI Osteoarthritis Research Society International
OXPHOS Oxidative phosphorylation
PAI-1 Plasminogen activator inhibitor-1
PGC1α Peroxisome proliferator-activated receptor-gamma coactivator
PI3K Phospho-inositole 3-kinase
PKM2 Piruvate kinase M2
PPAR Peroxisome Proliferator-Activated Recpetor
PTHrP Parathormone-related peptide
RAGE Receptor of end-glycation products
RANKL Receptor activator for nuclear factor kappa B ligand
ROS Reactive oxygen species
RunX2 Runt-related transcription factor 2
SASP Senescence-associated secretory pattern
SAV Salvador
SIRT 1,6 Sirtuin 1,6
SMAD Suppressor of mothers against Decapentaplegic
Sox-9 Sex-determining region Y-type (SRY) high mobility group (HMG) box family of DNA binding protein 9
STING Stimulator of interferon genes
TAZ Transcriptional coactivator with PDZ-binding motif
TCA Tricarboxylic acid cycle
TGF-β Transforming growth factor beta
TIMP-1 Tissue inhibitor of metalloproteinases 1
TLR-4 Toll-like Receptor 4
TNF-α Tumor necrosis factor alpha
TRPV4 Transient Receptor Potential Vanilloid 4
TSPYL2 Testis-specific Y-encoded-like protein 2
VEGF Vascular endothelial growth factor
YAP Yes-associated protein