Skip to main content
. 2023 Nov 18;24(22):16490. doi: 10.3390/ijms242216490

Figure 2.

Figure 2

The urine N-glycome was significantly different in LN compared to HC; some differed by sex. N-glycans were quantified in the same urine samples as in Figure 1 of 20 healthy controls (HC) and 20 lupus nephritis patients (LN) and included 10 females and 10 males in each group. N-glycan classes: high mannose (High Man), tetra-antennary (Tetra), sialylated (Sial), tri-antennary (Tri), fucosylated (Fucos), sulfated (Sulf), bisected (Bisect), bi-antennary (Bi), or Hybrid were compared in all HC vs. all LN (A) or by sex in each group (B). * Significant difference between HC and LN. Specific Q-values are provided in Table S1. Individual N-glycans were compared in all HC vs. all LN (C) or by sex in each group (D). Of the 72 individual N-glycans that differed significantly between HC and LN, the top 10 are presented in (C). Only three N-glycans differed significantly between females and males (D). (E) N-glycans associated with IgG are significantly different between HC and LN. N-glycan structures shown below the m/z peak values. See Table S2 for a list of all urine N-glycans detected and the adjusted Q values and Table S1 for N-glycans structure information.