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. 2023 Nov 18;24(22):16490. doi: 10.3390/ijms242216490

Figure 4.

Figure 4

The serum N-glycome was significantly different in LN compared to HC. N-glycans were quantified in the same serum samples as in Figure 3 of 20 healthy controls (HC) and 20 lupus nephritis patients (LN) and included 10 females and 10 males in each group. N-glycan classes: high mannose (High Man), tetra-antennary (Tetra), sialylated (Sial), tri-antennary (Tri), fucosylated (Fucos), sulfated (Sulf), bisected (Bisect), bi-antennary (Bi), or Hybrid were compared in all HC vs. all LN (A) or by sex in each group (C) * Q < 0.05 (see Table S3 for calculated adjusted Q-values). (B) Individual N-glycans were compared in all HC vs. all LN and the top 10 of the 21 individual N-glycans that differed significantly between HC and LN are presented. (D) N-glycans associated with IgG (ns, not significant).. N-glycan structures shown below the m/z peak values. See Table S3 for a list of all serum N-glycans detected and the calculated adjusted Q-values and Table S1 for N-glycans structures.