Table 2.

AUCs, likelihood ratio test (LRT) p-values, and differences in AUC of adding urine N-glycans to a “null” model. The null model included only total urine LacCers and biologic sex. Urine LacCers was natural log transformed prior to fitting the models to meet statistical assumptions. * Inclusion of this glycan yielded perfect separation of the cases and controls.

	AIC	LRT p-Value	AUC (95% CI)	Δ AUC (95% CI)
Null Model	43.12	0.0020	0.870 (0.748, 0.992)
2669 *	8	0.9970	1 (1, 1)	0.13 (0.008, 0.252)
1419 *	8	0.9976	1 (1, 1)	0.13 (0.008, 0.252)
1581 *	8	0.9987	1 (1, 1)	0.13 (0.008, 0.252)
Mannose *	8	0.9987	1 (1, 1)	0.13 (0.008, 0.252)
1485	33.92	0.0081	0.932 (0.859, 1.00)	0.062 (−0.031, 0.156)
1853	30.1	0.0081	0.945 (0.866, 1.00)	0.075 (−0.025, 0.175)
2174	32.47	0.0085	0.943 (0.876, 1.00)	0.073 (−0.036, 0.181)
1866	31.85	0.0095	0.948 (0.88, 1.00)	0.078 (−0.023, 0.178)
2122	33.54	0.0107	0.943 (0.872, 1.00)	0.073 (−0.047, 0.192)
2158	28.28	0.0108	0.958 (0.903, 1.00)	0.088 (−0.023, 0.198)
1996	31.62	0.0111	0.948 (0.887, 1.00)	0.078 (−0.026, 0.181)
2377	25.13	0.0119	0.970(0.923, 1.00)	0.100 (−0.019, 0.219)
2361	34	0.0124	0.938 (0.860, 1.00)	0.068 (−0.018, 0.153)
Tetraantennary	33.13	0.0130	0.938 (0.860, 1.00)	0.068 (−0.054, 0.189)
2012	34.74	0.0131	0.917 (0.830, 1.00)	0.047 (−0.062, 0.157)
2967	31.54	0.0159	0.943 (0.861, 1.00)	0.073 (−0.042, 0.187)
2289	36.13	0.0170	0.915 (0.828, 1.00)	0.045 (−0.059, 0.149)
Sialylation	35.54	0.0182	0.948 (0.874, 1.00)	0.078 (−0.018, 0.173)
1831	34.34	0.0212	0.932 (0.846, 1.00)	0.062 (−0.014, 0.139)
2056	37.2	0.0225	0.915 (0.829, 1.00)	0.045 (−0.025, 0.115)
1704	33.24	0.0242	0.955 (0.886, 1.00)	0.085 (−0.011, 0.181)
1809	37.7	0.0250	0.917 (0.833, 1.00)	0.047 (−0.036, 0.131)
3770	37.38	0.0264	0.902 (0.805, 1.00)	0.032 (−0.062, 0.127)
2632	38.17	0.0289	0.907 (0.813, 1.00)	0.037 (−0.035, 0.110)
2487	38.8	0.0311	0.897 (0.806, 0.989)	0.027 (−0.065, 0.120)
2267	37.86	0.0314	0.915 (0.830, 1.00)	0.045 (−0.038, 0.128)
1257	20.36	0.0346	0.985 (0.959, 1.00)	0.115 (−0.005, 0.235)
2245	38.88	0.0363	0.902 (0.807, 0.998)	0.032 (−0.034, 0.099)
2852	38.39	0.0367	0.912 (0.823, 1.00)	0.042 (−0.068, 0.153)
1079	39.5	0.0372	0.900 (0.793, 1.00)	0.030 (−0.067, 0.127)
2221	39.48	0.0389	0.902 (0.807, 0.998)	0.032 (−0.047, 0.112)
2638	38.44	0.0406	0.910 (0.809, 1.00)	0.040 (−0.040, 0.120)
3333	38.94	0.0412	0.897 (0.800, 0.995)	0.027 (−0.070, 0.125)
2287	38.33	0.0445	0.902 (0.808, 0.997)	0.032 (−0.040, 0.105)
1663	39.57	0.0477	0.885 (0.774, 0.996)	0.015 (−0.032, 0.062)
1891	19.61	0.0557	0.988 (0.965, 1.00)	0.118 (−0.001, 0.236)
1743	19.12	0.0567	0.985 (0.957, 1.00)	0.115 (0.005, 0.225)
2945	40.2	0.0586	0.897 (0.801, 0.994)	0.027 (−0.032, 0.087)
1905	21.5	0.0604	0.983 (0.954, 1.00)	0.113 (0.001, 0.224)
1444	37.27	0.0657	0.920 (0.831, 1.00)	0.05 (−0.038, 0.138)
2465	41.09	0.0714	0.890 (0.792, 0.988)	0.02 (−0.053, 0.093)
1960	41.41	0.0741	0.887 (0.774, 1.00)	0.017 (−0.038, 0.073)
2523	37.65	0.0813	0.907 (0.809, 1.00)	0.037 (−0.024, 0.099)
3144	40.32	0.0826	0.897 (0.800, 0.995)	0.027 (−0.05, 0.105)
1647	41.44	0.0864	0.895 (0.798, 0.992)	0.025 (−0.04, 0.09)
3646	41.69	0.0948	0.887 (0.787, 0.988)	0.017 (−0.043, 0.078)
2654	41.54	0.1038	0.887 (0.779, 0.996)	0.017 (−0.059, 0.094)
1954	42.03	0.1056	0.892 (0.790, 0.995)	0.022 (−0.036, 0.081)
2610	41.41	0.1125	0.885 (0.777, 0.993)	0.015 (−0.038, 0.068)
2028	42.3	0.1158	0.893 (0.778, 1.00)	0.023 (−0.024, 0.069)
sulfation	42.4	0.1233	0.900 (0.793, 1.00)	0.03 (−0.016, 0.076)
2163	42.2	0.1234	0.882 (0.774, 0.991)	0.012 (−0.062, 0.087)
2923	42.01	0.1353	0.880 (0.774, 0.986)	0.01 (−0.052, 0.072)
1814	42.61	0.1363	0.885 (0.786, 0.984)	0.015 (−0.061, 0.091)
2304	42.78	0.1480	0.887 (0.784, 0.991)	0.017 (−0.057, 0.092)
3092	42.8	0.1579	0.873 (0.754, 0.991)	0.003 (−0.034, 0.039)
1850	42.93	0.1609	0.88 (0.771, 0.989)	0.01 (−0.059, 0.079)
3193	42.38	0.1649	0.885 (0.778, 0.992)	0.015 (−0.042, 0.072)
3113	42.56	0.1651	0.882 (0.769, 0.996)	0.012 (−0.017, 0.042)
3004	42.8	0.1815	0.878 (0.760, 0.995)	0.008 (−0.03, 0.045)
2435	43.22	0.1838	0.875 (0.769, 0.981)	0.005 (−0.06, 0.07)
3093	43.2	0.1933	0.865 (0.740, 0.990)	−0.005 (−0.039, 0.029)
2393	43.16	0.2030	0.880 (0.769, 0.991)	0.010 (−0.042, 0.062)
fucosylation	43.35	0.2073	0.885 (0.780, 0.990)	0.015 (−0.044, 0.074)
2100	43.33	0.2168	0.870 (0.754, 0.986)	0.00 (−0.048, 0.048)
3384	43.18	0.2193	0.873 (0.755, 0.99)	0.003 (−0.044, 0.049)
triantennary	43.7	0.2642	0.870 (0.747, 0.993)	0.00 (−0.052, 0.052)
bisect	43.82	0.2776	0.882 (0.774, 0.991)	0.012 (−0.045, 0.07)
2319	43.58	0.2828	0.882 (0.772, 0.993)	0.012 (−0.036, 0.061)
1875	44.09	0.3257	0.882 (0.769, 0.996)	0.012 (−0.017, 0.042)
2383	44.55	0.4570	0.882 (0.767, 0.998)	0.012 (−0.019, 0.044)
2413	44.69	0.5224	0.863 (0.739, 0.986)	−0.007 (−0.041, 0.026)
1773	44.75	0.5600	0.875 (0.756, 0.994)	0.005 (−0.016, 0.026)
1611	44.83	0.5933	0.877 (0.762, 0.993)	0.007 (−0.02, 0.035)
2594	44.87	0.6229	0.877 (0.759, 0.996)	0.007 (−0.019, 0.034)
2339	44.89	0.6393	0.875 (0.752, 0.998)	0.005 (−0.019, 0.029)
2341	44.97	0.7073	0.875 (0.758, 0.992)	0.005 (−0.019, 0.029)
2391	45.1	0.9027	0.873 (0.750, 0.995)	0.003 (−0.004, 0.009)