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. 2023 Nov 10;13(11):1595. doi: 10.3390/jpm13111595
NHL non-Hodgkin lymphoma
B-NHL B-cell non-Hodgkin lymphoma
BL Burkitt lymphoma
DLBCL diffuse large B-cell lymphoma
CNS central nervous system
OS overall survival
mAb monoclonal antibody
ICI immune checkpoint inhibitor
ADC antibody–drug conjugate
CAR chimeric antigen receptor
MHC major histocompatibility complex
CD cluster of differentiation
TCR T cell receptor
ITAM immuno-tyrosine activation motif
ICOS inducible T cell co-stimulator
IL interleukin
FDA Food and Drug Administration
EMA European Medicines Agency
R/R relapsed or refractory
ORR overall response rate
CRR complete response rate
CR complete response
PRR partial response rate
PR partial response
DOR duration of response
PFS progression-free survival
CRS cytokine release syndrome
FL follicular lymphoma
LBCL large B-cell lymphoma
tisa-cel tisagenlecleucel
HGBCL high-grade B-cell lymphoma
tFL transformed follicular lymphoma
auto-HSCT autologous hematopoietic stem-cell transplantation
ALL acute lymphoblastic leukemia
axi-cel axicabtagene ciloleucel
KTE X19-Brexucabtagene autoleucel
liso-cel lisocabtagene maraleucel
DLT dose-limiting toxicities
CLL chronic lymphocytic leukemia
SLL small lymphocytic lymphoma
LDH lactate dehydrogenase
HRQoL health-related quality of life
EORTC QLQ-C30-European Organization for Research and Treatment of Cancer Quality of Life Questionnaire
QoL Quality of Life
PET Positron-Emission Tomography
PET-CT-Positron Emission Tomography and Computed Tomography
PTLD-post-transplant B-cell lymphoproliferative disorder
allo-HSCT-allogeneic hematopoietic stem cell transplantation
ctDNA-cell-free circulating tumor DNA
AE-adverse effect
ICANS immune effector cell-associated neurotoxicity syndrome
CRES CAR-T-cell-related encephalopathy syndrome
TLS tumor lysis syndrome
TNF α-tumor necrosis factor-alpha
ICU intensive care unit
CRP C-reactive protein
CBC complete blood count
DIC disseminated intravascular coagulation
BBB blood–brain barrier
ICE immune effector cell-associated encephalopathy
EEG electroencephalography
CMV cytomegalovirus
EBV Epstein–Barr virus
HHV6 human herpesvirus 6
HSV herpes simplex virus
HBV hepatitis B virus
PJP Pneumocystis jirovecii
HLH hemophagocytic lymphohistiocytosis
G-CSF granulocyte colony-stimulating factor
IVIG intravenous immunoglobulin
G6PD glucose-6-phosphate dehydrogenase
TME tumor microenvironment
TB tumor burden
IFN-ɣ interferon-gamma
HL hodgkin lymphoma