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. 2023 Nov 20;24(22):16523. doi: 10.3390/ijms242216523

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Schematic presentation of the endocannabinoid system. The endocannabinoid system consists of endocannabinoids, receptors, and enzymes. Cannabidiol (CBD) and Δ-9-tetrahydrocannabinol (THC) are phytocannabinoids, and palmitoylethanolamide (PEA) and 2-arachidonoyl-glycerol (2-AG) are endocannabinoids. CB1R, cannabinoid receptor 1; CB2R, cannabinoid receptor 2; TRP, transient receptor potential; CBD, cannabidiol; THC, Δ-9-tetrahydrocannabinol; PEA, palmitoylethanolamide; 2-AG, 2-arachidonoyl-glycerol. This figure was created with Biorender at www.biorender.com (accessed on 21 August 2023).