TABLE 5.

Sequence similarities between proteins that (putatively) provide immunity to class IIa bacteriocins^a

Immunity protein	% Identity or similarity to:
	CarBM1	SakA	CarB2	Orf-β3	SakP	LeuA	MesY105	EntA	OrfY	PedPA-1	EntP	Bac31
CarBM1		49	19	17	18	20	20	19	24	25	44	50
SakA (2)	65		19	19	17	21	24	21	22	18	47	42
CarB2 (39)	31	33		26	23	11	12	15	18	5	19	24
Orf-β3	31	31	37		46	28	22	27	22	21	20	22
SakP (25)	25	22	34	62		18	18	12	17	17	23	17
LeuA (49)	38	32	21	38	32		73	38	40	11	22	21
MesY105	35	32	20	41	29	81		40	36	9	20	22
EntA	31	31	19	40	19	50	47		27	20	14	17
OrfY	35	29	27	36	26	51	45	39		14	17	16
PedPA-1 (50)	35	39	19	27	28	20	18	31	23		19	22
EntP	59	58	33	31	31	35	32	25	28	30		52
Bac31	66	54	31	32	30	30	32	29	21	34	67

^aSequence identity (upper-right triangle) and similarity (lower-left triangle) between proteins that (putatively) provide immunity to class IIa bacteriocins are shown. References are given for proteins for which the immunity function has been demonstrated through functional studies. The proteins displayed are the (putative) immunity proteins for carnobacteriocin BM1 (CarBM1) (38), carnobacteriocin B2 (CarB2) (38, 39), sakacin A (SakA) (2), sakacin P (SakP) (25), leucocin A (LeuA) (22, 49), enterocin A (EntA) (3), mesentericin Y105 (MesY105) (19), pediocin PA-1 (PedPA-1) (32, 50), enterocin P (EntP) (11), and bacteriocin 31 (Bac31) (47). Other putative immunity proteins shown are the products of orfY (see the text) and of orf-β3 (an open reading frame that follows the genes encoding carnobacteriocin B2 and the CarB2 immunity protein) (38).