Table 6.
Impact of CVD risk factors not included in the ASCVD Risk Calculator on the development of CVD.
| Model | Variables | ASCVD Risk Calculator | ||||
|---|---|---|---|---|---|---|
| OR | −95%CI | +95%CI | Wald’s Statistics | p-Value | ||
| Model 1 | Intercept | 0.164 | 0.079 | 0.342 | 23.202 | <0.001 |
| General obesity | 0.000 | 0.000 | 0.000 | 1213.184 | <0.001 | |
| Abdominal obesity | 1.128 | 0.502 | 2.535 | 0.086 | 0.770 | |
| Model 2 | Intercept | 0.001 | 0.000 | 0.041 | 11.431 | 0.001 |
| WC [cm] | 1.000 | 0.964 | 1.038 | 0.000 | 0.987 | |
| HbA1c [%] | 2.748 | 1.626 | 4.643 | 14.258 | <0.001 | |
| TG [mg/dL] | 1.001 | 0.992 | 1.011 | 0.085 | 0.771 | |
| Model 3 | Intercept | 0.077 | 0.017 | 0.343 | 11.309 | 0.001 |
| Mets (no MetS vs. pre-Mets) |
1.484 | 0.316 | 6.972 | 0.250 | 0.617 | |
| Mets (no MetS vs. Mets) | 19.138 | 3.522 | 103.979 | 11.684 | 0.001 | |
| BDI (score) | 1.012 | 0.956 | 1.072 | 0.171 | 0.679 | |
| Model 4 | Intercept | 0.066 | 0.014 | 0.312 | 11.763 | 0.001 |
| General obesity | 0.000 | 0.000 | 0.000 | 822.633 | <0.001 | |
| Abdominal obesity | 0.562 | 0.205 | 1.540 | 1.254 | 0.263 | |
| Mets (no MetS vs. pre-Mets) |
1.794 | 0.342 | 9.418 | 0.478 | 0.489 | |
| Mets (no MetS vs. Mets) | 25.623 | 3.885 | 169.002 | 11.357 | 0.001 | |
| BDI (score) | 1.022 | 0.964 | 1.082 | 0.520 | 0.471 | |
OR—odds ratio, CI—confidence interval, WC—waist circumference, HbA1c—glycated hemoglobin, TG—triglycerides, MetS—metabolic syndrome, BDI—Beck Depression Inventory. Model 0—could not be created because there was no increased risk of CVD among perimenopausal women. Model 1—model adjusted for the variables: general and abdominal obesity. Model 2—model adjusted for the variables: WC, HBA1C, TG. Model 3—model adjusted for the variables: diabetes, MetS, BDI score. Model 4—model adjusted for the variables: general and abdominal obesity, MetS, BDI score.