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Cells and cytotoxicity (n = 6). (A) Cytotoxicity assay using HT-29 and HRT-18 cells treated with blank nanoparticles. (B) Cytotoxicity assay using HT-29 and HRT-18 cells treated with HA-PLGA-API-NPs. (C) Cytotoxicity of free API and different modified nanoparticles towards HT-29 cells. The data are presented as means ± SD, n = 3, * p < 0.05, ** p < 0.01.
