Table 5.
Effects of AEUD and MESA on serum metabolic and biochemical parameters in diverse groups.
| Groups | Control | DSS | DSS + AEUD-50 | DSS + AEUD-100 | DSS + AEUD-200 | DSS + MESA | 
|---|---|---|---|---|---|---|
| CRP (mg/L) | 0.37 ± 0.08 | 2.05 ± 0.15 * | 0.42 ± 0.05 # | 0.83 ± 0.16 # | 1.24 ± 0.16 # | 0.5 ± 0.08 # | 
| Amylase (U/L) | 225 ± 14.86 | 1047 ± 40.66 * | 831.66 ± 31.25 # | 854 ± 38.04 # | 825 ± 22.64 # | 785.5 ± 37.34 # | 
| Urea (mmol/L) | 4.47 ± 0.33 | 6.46 ± 0.2 * | 6.06 ± 0.36 | 6.17 ± 0.57 | 6.01 ± 0.29 | 6.02 ± 0.67 | 
| Creatinine (µmol/L) | 37.5 ± 1.29 | 45.83 ± 1.6 * | 45.16 ± 2.13 | 45.83 ± 3.06 | 46.4 ± 3.91 | 40.5 ± 2.42 | 
| AST (U/L) | 85.75 ± 2.98 | 189.16 ± 15.94 * | 89.2 ± 2.58 # | 91.5 ± 2.07 # | 94.75 ± 3.3 # | 105.33 ± 8.35 # | 
| ALT (U/L) | 37.5 ± 2.64 | 59.66 ± 6.97 * | 49.16 ± 1.16 # | 42.83 ± 3.18 # | 40.25 ± 2.87 # | 56 ± 3.89 # | 
| ALP (U/L) | 59.75 ± 3.3 | 141.2 ± 4.08 * | 91.6 ± 1.51 # | 86.4 ± 3.84 # | 88.6 ± 2.3 # | 84 ± 3.31 # | 
| LDH (U/L) | 414.4 ± 22.46 | 971.83 ± 63.12 * | 901.75 ± 4.34 | 949.4 ± 62.3 | 870.25 ± 31.48 | 666.33 ± 36.43 | 
| TC (mmol/L) | 1.23 ± 0.33 | 1.24 ± 0.19 | 1.14 ± 0.34 | 1.14 ± 0.21 | 1.06 ± 0.08 | 1.17 ± 0.17 | 
| TG (mmol/L) | 0.95 ± 0.07 | 1.005 ± 0.14 | 0.64 ± 0.08 | 0.62 ± 0.05 | 0.94 ± 0.06 | 0.86 ± 0.08 | 
| HDL (mmol/L) | 0.59 ± 0.06 | 0.49 ± 0.04 | 0.5 ± 0.05 | 0.52 ± 0.04 | 0.5 ± 0.06 | 0.56 ± 0.06 | 
| LDL (mmol/L) | 0.23 ± 0.04 | 0.32 ± 0.03 | 0.26 ± 0.04 | 0.3 ± 0.03 | 0.32 ± 0.04 | 0.22 ± 0.06 | 
| Glu (mmol/L) | 7.16 ± 0.5 | 7.87 ± 0.42 | 5.35 ± 0.48 # | 5.69 ± 0.22 # | 5.48 ± 0.29 # | 7.09 ± 0.5 | 
| Sodium (mEq/L) | 131.2 ± 0.83 | 137 ± 1.41 | 136.66 ± 2.94 | 136.16 ± 2.63 | 137.2 ± 3.34 | 135.66 ± 3.44 | 
| Potassium (mEq/L) | 5.79 ± 0.48 | 6.1 ± 0.71 | 6.96 ± 0.86 | 6.96 ± 0.41 | 6.26 ± 0.53 | 5.75 ± 0.62 | 
Data are expressed as mean ± SEM (n = 6). * p < 0.05 compared to control group, # p < 0.05 compared to DSS group.